摘要
The novel coronavirus disease 2019(COVID-19)was firstly reported in Wuhan,China,and eventually identified on December 31,2019 and remains as an ongoing worldwide pandemic.Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)invades human alveolar epithelial cells in the nose and throat mainly through angiotensin-converting enzyme 2(ACE2),[1]inducing innate inflammation in the lungs largely mediated by pro-inflammatory macrophages and granulocytes.
基金
This work is partially supported by British Heart Foundation(PG/18/14/33562)
National Institute for Health Research Cambridge Biomedical Research Centre,National Natural Science Foundation of China(81871354,81571672)
the Taishan Scholar Projection,and Academic Promotion Programme of Shandong First Medical University(2019QL023).
