摘要
目的:系统评价食管癌病人术后肺部感染的危险因素。方法:计算机检索中国知网(CNKI)、万方数据库(WangFang Database)、维普(VIP)、中国生物医学文献数据库(CBM)、PubMed、The Cochrane Library、Web of Science、Embase数据库,收集建库至2021年6月发表的相关文献,按纳入标准与排除标准进行文献筛选,应用RevMan 5.3软件进行Meta分析。结果:共纳入18篇文献,累计纳入食管癌病人4 673例。Meta分析结果显示,年龄[OR=1.67,95%CI(1.35,2.06),P<0.000 01]、吸烟史[OR=3.41,95%CI(1.56,7.46),P=0.002]、合并基础疾病[OR=4.27,95%CI(2.13,8.55),P<0.000 1]、糖尿病[OR=2.45,95%CI(1.99,3.01),P<0.000 01]、并发症[OR=2.68,95%CI(1.04,6.92),P=0.04]、喉返神经损伤[OR=4.14,95%CI(2.84,6.04),P<0.000 01]、COPD[OR=2.96,95%CI(1.84,4.76),P<0.000 1]、术前营养不良[OR=3.46,95%CI(1.89,6.35),P<0.000 1]、血清白蛋白低[OR=3.95,95%CI(1.91,8.17),P=0.000 2]、抑酸剂应用时间[OR=5.03,95%CI(2.31,10.93),P<0.000 1]、住院天数[OR=2.36,95%CI(1.57,3.54),P<0.000 1]为食管癌病人术后肺部感染的危险因素。结论:针对主要危险因素为病人制定预防措施,加强呼吸道管理,有利于降低病人术后肺部感染发生率。
Objective:To systematically evaluate the risk factors of postoperative pulmonary infection in patients with esophageal cancer.Methods:CNKI,WangFang Database, VIP,CBM,PubMed, The Cochrane Library, Web of Science and Embase databases were searched by computer.Relevant literatures published from the establishment of the database to June 2021 were collected and screened according to inclusion and exclusion criteria.Meta-analysis was conducted by RevMan 5.3 software.Results:A total of 18 literatures were included, including 4 673 patients with esophageal cancer.Meta-analysis results showed that, Age[OR=1.67,95%CI(1.35,2.06),P<0.000 01],smoking history[OR=3.41,95%CI(1.56,7.46),P=0.002],with underlying diseases[OR=4.27,95%CI(2.13,8.55),P<0.000 1],diabetes[OR=2.45,95%CI(1.99,3.01),P<0.000 01],complications [OR=2.68,95%CI(1.04,6.92),P=0.04],laryngeal recurrent nerve injury[OR=4.14,95%CI(2.84,6.04),P<0.000 01],COPD[OR=2.96,95%CI(1.84,4.76),P<0.000 1],preoperative malnutrition[OR=3.46,95%CI(1.89,6.35),P<0.000 1],low serum albumin[OR=3.95,95%CI(1.91,8.17),P=0.000 2],application time of antacids[OR=5.03,95%CI(2.31,10.93),P<0.000 1],length of stay[OR=2.36,95%CI(1.57,3.54),P<0.000 1] were risk factors for postoperative pulmonary infection in patients with esophageal cancer.Conclusion:According to the main risk factors for patients to formulate preventive measures, strengthen the management of respiratory tract, is conducive to reduce the incidence of postoperative pulmonary infection.
作者
廖佳倩
王国蓉
邓晓园
陈寿莉
LIAO Jiaqian;WANG Guorong;DENG Xiaoyuan;CHEN Shouli(Chengdu University of Traditional Chinese Medicine,Sichuan 610036 China)
出处
《全科护理》
2022年第9期1163-1167,共5页
Chinese General Practice Nursing
关键词
食管癌
术后
肺部感染
危险因素
META分析
esophageal cancer
postoperative
pulmonary infection
risk factors
Meta-analysis
