摘要
目的:探讨不同治疗方案对大脑中动脉M1段分叉动脉瘤患者近期疗效及对术后感染、复发情况的影响分析。方法:回顾性分析2015年2月至2020年2月期间收治的46例大脑中动脉M1段分叉动脉瘤患者的临床资料,根据治疗方案分为开颅手术组(26例)、介入栓塞组(20例)。比较两组患者手术相关指标、近期疗效,术后随访1年,记录两组患者术后感染、复发情况。结果:介入栓塞组患者手术时间、术中出血量、住院时间均明显小于开颅手术组患者,治疗费用明显高于开颅手术组患者,差异具有统计学意义(均P<0.05);术后1、3个月,两组患者临床疗效比较,差异无统计学意义(均P>0.05),两组患者术后3个月临床疗效均明显优于术后1个月,差异具有统计学意义(均P<0.05);开颅手术组患者术后感染率高于介入栓塞组患者(15.38%vs5.00%),而术后复发率低于介入栓塞组患者(0.00%vs10.00%),但组间比较,差异无统计学意义(均P>0.05)。结论:开颅夹闭手术与血管内介入栓塞术治疗大脑中动脉M1段分叉动脉瘤患者近期疗效均尚可,前者具有术后复发率、治疗费用低优点,后者具有术后感染率低、住院时间短优点,临床中应结合患者实际情况及经济状况选择最优治疗方案。
Objective:To explore the short-term curative effect of different treatment regimens for patients with M1 bifurcation aneurysm of the middle cerebral artery and their influence on postoperative infection and recurrence.Methods:The clinical data of 46 patients with middle cerebral artery M1 bifurcation aneurysm who were treated between February 2015 and February 2020 were retrospectively analyzed.According to the treatment regimens,they were divided into craniotomy group(26 cases)and interventional embolization group(20 cases).The operation-related indicators and short-term efficacy of the two groups were compared.The patients were followed up for 1 year,and the postoperative infection and recurrence were recorded.Results:The operation time,intraoperative blood loss and hospital stay in the interventional embolization group were significantly shorter,and the treatment cost was significantly higher than those in the craniotomy group,and the differences were statistically significant(All P<0.05).At 1 and 3 months after surgery,there was no significant difference in the clinical efficacy between the two groups of patients(All P>0.05).The clinical efficacy of the two groups at 3 months after surgery was significantly better than that at 1 month after surgery,and the difference was statistically significant(All P>0.05);the postoperative infection rate in the craniotomy group was higher than that in the interventional embolization group(15.38%vs 5.00%),while the postoperative recurrence rate was lower than that in the interventional embolization group(0.00%vs 10.00%),but there was no significant difference between groups(All P>0.05).Conclusion:Both craniotomy and interventional embolization for the treatment of middle cerebral artery M1 bifurcated aneurysms have good short-term curative effects.The former has the advantages of lower postoperative recurrence rate and lower treatment cost,and the latter has lower postoperative infection rate and shorter hospitalization.The optimal treatment regimen should be chosen in the
作者
宾再青
尹佃敏
唐奇勇
BIN Zaiqing;YIN Dianmin;TANG Qiyong(Hunan Provincial Hospital of Traditional Chinese Medicine, Hunan Zhuzhou 412000, China)
出处
《河北医学》
CAS
2022年第3期398-402,共5页
Hebei Medicine
基金
湖南省卫生健康委2020年度科研顶课题,(编号:20201873)。
关键词
开颅手术
介入栓塞术
大脑中动脉M1段分叉动脉瘤
Craniotomy
Interventional embolization
M1 bifurcation aneurysm of middle cerebral artery
