摘要
目的总结本中心合并冠状动脉壁内走行(intramural coronary artery, IMCA)的完全性大动脉转位(transposition of the great arteries,TGA)婴儿患者的手术经验,并分析其早期和中期临床结果。方法回顾性分析2010年6月—2018年12月于阜外医院接受大动脉调转术(arterial switch operation,ASO)384例TGA患儿的临床资料。根据手术记录,21例(5.5%)婴儿合并有IMCA,其中20例(95.2%)为男性,中位手术年龄为33(9~319)d。所有患者均采用壁内冠状动脉去顶及双纽扣法冠状动脉再植进行ASO。结果合并IMCA的患者与正常冠状动脉解剖的患者相比,ASO术后早期死亡率差异无统计学意义(9.5%vs. 3.0%,P=0.15)。IMCA组2例死亡患者首次开放循环后均出现冠状动脉灌注不良。此外,还有1例患者因心功能不全行体外膜肺支持治疗。19例存活出院的患者均得到随访,平均随访时间为29.0~120.0(74.8±27.3)个月。随访期间,所有患者均无明显症状,且未出现死亡、二次手术及冠状动脉并发症。其中1例患者出现肺动脉瓣中度反流,另1例患者出现右肺动脉远端狭窄。结论对合并IMCA的TGA婴儿患者,采用壁内冠状动脉去顶及双纽扣法冠状动脉再植进行ASO安全可靠,早期及中期结果满意。
Objective To summarize the surgical experience of infants with transposition of the great arteries(TGA) and intramural coronary artery(IMCA) in our center, and analyze the early and mid-term outcomes. Methods We retrospectively analyzed the clinical data of 384 infants with TGA undergoing arterial switch operation(ASO) from June2010 to December 2018 at Fuwai Hospital. According to operative records, 21(5.5%) infants had IMCA, among whom 20 were males, with a median age of 33(9-319) d. Coronary transfer using double coronary buttons with unroofed intramural course was performed in all 21 infants. Results There was no statistical difference in the early mortality after ASO between infants with IMCA and infants with normal coronary anatomy(9.5% vs. 3.0%, P=0.15). In the IMCA group, 2 dead patients presented inadequate coronary artery perfusion after first aortic unclamping. In addition, 1 patient underwent extracorporeal membrane pulmonary support for myocardial dysfunction. The follow-up was available for all19 survivors, with an average follow-up time of 29.0-120.0(74.8±27.3) months. During the follow-up, all patients had no obvious symptoms, death, reoperation, or coronary complications. One patient developed moderate pulmonary valve regurgitation and another patient developed distal stenosis of the right pulmonary artery. Conclusion For infants with TGA and IMCA, coronary transfer using double coronary buttons with unroofed intramural course is a safe and reliable technique, with satisfactory early and mid-term outcomes.
作者
顿耀军
孙海宁
闫军
杨克明
花中东
王强
李守军
DUN Yaojun;SUN Haining;YAN Jun;YANG Keming;HUA Zhongdong;WANG Qiang;LI Shoujun(Department of Cardiovascular Surgery,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences,Beijing,100037,P.R.China)
出处
《中国胸心血管外科临床杂志》
CSCD
北大核心
2022年第3期323-329,共7页
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
