摘要
目的探讨丁苯酞注射液在分水岭脑梗死患者中的治疗效果及对认知水平的影响。方法便利选取2019年1—12月该院收治的98例分水岭脑梗死患者为研究对象,并随机分为研究组和对照组。每组49例。对照组采取常规治疗,研究组在对照组基础上联合丁苯酞注射液治疗。对两组疗效、治疗前后认知功能及日常生活能力改善情况进行分析对比,比较两组治疗前、后的生活质量评分。结果与对照组(67.34%)相比研究组治疗总有效率(87.75%)较高,差异有统计学意义(χ^(2)=5.861,P<0.05);研究组治疗后的简明精神状态量表(MMSE)评分(26.6±2.3)分及Bathel指数(70.4±3.4)分均高于对照组(20.3±2.0)分、(55.0±3.2)分,差异有统计学意义(t=14.469、23.008,P<0.05);研究组治疗后的社会、躯体、角色及认知功能评分分别为(80.3±4.6)分、(80.2±4.0)分、(81.3±5.3)分、(80.4±4.6)分均高于对照组的(74.0±5.0)分、(71.0±3.5)分、(71.4±4.0)分、(74.1±3.7)分,差异有统计学意义(t=6.491、12.116、10.436、7.470,P<0.05)。结论对分水岭脑梗死患者采用丁苯酞注射液治疗,其效果较好,并能够促使患者的认知功能及日常生活能力得到显著改善。
Objective To investigate the therapeutic effect of butylphthalide injection in patients with watershed cerebral infarction and its influence on cognition.Methods A total of 98 patients with watershed cerebral infarction admitted to the hospital from January to December 2019 were conveniently selected as the research objects,and they were randomly divided into a study group and a control group.Each group had 49 cases.The control group took conventional treatment,and the study group was treated with butylphthalide injection on the basis of the control group.The efficacy,cognitive function and the improvement of daily living ability of the two groups before and after treatment were analyzed and compared,the quality of life scores of the two groups before and after treatment were compared.Results Compared with the control group(67.34%),the study group(87.75%)had a higher total effective rate of treatment,the difference was statistically significant(χ^(2)=5.861,P<0.05).The MMSE score(26.6±2.3)points and Bathel index(70.4±3.4)points of the study group after treatment were higher than those of the control group(20.3±2.0)points,(55.0±3.2)points,the difference was statistically significant(t=14.469,23.008,P<0.05).The scores of social,physical,role and cognitive function of the study group after treatment were(80.3±4.6)points,(80.2±4.0)points,(81.3±5.3)points,(80.4±4.6)points were higher than those of the control group(74.0±5.0)points,(71.0±3.5)points,(71.4±4.0)points,(74.1±3.7)points,the difference was statistically significant(t=6.491,12.116,10.436,7.470,P<0.05).Conclusion The use of butylphthalide injection to treat patients with watershed cerebral infarction has a good effect,and can promote the patients'cognitive function and ability of daily living to be significantly improved.
作者
李鑫
贺博
LI Xin;HE Bo(Department of Neurology,Liaocheng Fourth People's Hospital,Liaocheng,Shandong Province,252000 China)
出处
《中外医疗》
2022年第1期84-87,共4页
China & Foreign Medical Treatment
关键词
丁苯酞注射液
分水岭脑梗死
治疗效果
认知水平
Butylphthalide injection
Watershed cerebral infarction
Therapeutic effect
Cognitive level
