摘要
目的探讨兴孢哌酮钠舒巴坦钠联合氨溴索、特布他林治疗小儿支气管肺炎的临床疗效。方法随机选取该院2019年3月—2020年3月期间收治的支气管肺炎患儿80例,采用随机数表法分为研究组40例和对照组40例,对照组患儿接受头孢、特布他林进行治疗,研究组患儿在对照组基础上联用氨溴索进行治疗,对比两组患儿临床疗效,治疗后临床指标(退热时间、住院时间和啰音消失时间),治疗前后血常规指标水平(中性粒细胞百分比、白细胞计数及淋巴细胞百分比),治疗前后血液CRP、PCT情况。结果研究组总有效率为97.5%,高于对照组的80.0%,差异有统计学意义(χ^(2)=4.507,P=0.034),研究组退热时间(3.12±1.24)d、住院时间(5.21±1.14)d和啰音消失时间(4.21±0.98)d短于对照组,差异有统计学意义(t=4.154、4.665、6.251,P<0.05);两组治疗前白细胞计数、中性粒细胞和淋巴细胞百分比对比差异无统计学意义(P>0.05),治疗后,研究组白细胞计数(6.85±1.22)×109/L、中性粒细胞百分比(39.31±10.62)%和淋巴细胞百分比(60.33±15.65)%优于对照组,差异有统计学意义(t=4.027、5.441、7.457,P<0.05);治疗前,两组CRP、PCT水平差异无统计学意义(P>0.05),治疗后研究组CRP(12.21±4.32)mg/L、PCT(1.52±0.55)μg/L低于对照组,差异有统计学意义(t=7.582、4.657,P<0.05)。结论给予支气管肺炎患儿头孢哌酮钠舒巴坦钠联合氨溴索、特布他林进行治疗,临床效果较为显著且有利于减少患儿的退热时间和住院时间,很大程度地改善了患儿的临床指标,降低患儿血清CRP和PCT水平。
Objective To explore the clinical efficacy of sporparin sodium and sulbactam sodium combined with ambroxol and terbutaline in the treatment of bronchial pneumonia in children.Methods A total of 80 children with bronchial pneumonia admitted to the hospital from March 2019 to March 2020 were randomly selected.Using random number table method,they were divided into 40 cases in the study group and 40 cases in the control group.Children in the control group received cephalosporin and terbutaline for treatment,and children in the study group were treated with ambroxol on the basis of the control group.Compared the clinical efficacy of the two groups of children,the clinical indicators of the two groups of children after treatment(the time to fever,the length of hospitalization,and the time for the disappearance of rales).The blood routine index levels of the two groups of children before and after treatment(percentage of neutrophils,white blood cell count and lymphocyte percentage)The blood CRP and PCT of the two groups of children before and after treatment.Results The total effective rate in the study group was 97.5%,which was higher than 80.0%in the control group,the difference was statistically significant(χ^(2)=4.507,P=0.034).The antipyretic time(3.12±1.24)d,hospital stay(5.21±1.14)d and rale disappearance time(4.21±0.98)d in the study group were shorter than those in the control group,the difference was statistically significant(t=4.154,4.665,6.251,P<0.05);there was no statistically significant difference in leukocyte count,neutrophil and lymphocyte percentage between the two groups before treatment(P>0.05).After treatment,the leukocyte count in the study group was(6.85±1.22)×109/L,the percentage of neutrophils(39.31±10.62)%and the percentage of lymphocytes(60.33±15.65)%were better than those in the control group,and the difference was statistically significant(t=4.027,5.441,7.457,P<0.05);there was no statistically significant difference in the levels of CRP and PCT between the two groups before treatment
作者
冼飞鸣
XIAN Feiming(Department of General Pediatrics,Maternal and Child Health Hospital,Duanzhou District,Zhaoqing,Guangdong Province,526040 China)
出处
《中外医疗》
2022年第2期107-110,共4页
China & Foreign Medical Treatment
