摘要
输血已经成为现在临床治疗的1个重要辅助手段,但是输血并不是1个安全无风险的治疗方法,输血相关的红细胞同种抗体是其潜在的1个较大风险。在我国汉族人群中红细胞同种抗体检出率约0.2%,但因其在患者将来的输血或妊娠中具有重要的临床意义,对其产生机制的探索和研究显得尤为关键,我们将对目前输血相关红细胞同种抗体及其易感因素的研究情况进行综述。
Blood transfusion, an important auxiliary means of clinical treatment, however, is not absolutely safe and risk-free as the transfusion-associated RBC alloantibodies being a potential risk. The yielding rate of RBC alloantibodies in Chinese Han population is about 0.2%, and the researches concerning its production mechanism is particularly critical due to its important clinical significance in patients′ future blood transfusion or pregnancy. This paper reviews the current research status of red blood cell alloantibodies associated with blood transfusion and its susceptibility factors.
作者
谢宇頔
田力
刘忠
XIE Yudi;TIAN Li;LIU Zhong(Institute of Blood Transfusion,Chinese Academy of Medical Sciences and Peking Union Medical College,Chengdu 610052,China)
出处
《中国输血杂志》
CAS
2022年第2期233-236,共4页
Chinese Journal of Blood Transfusion
基金
中国医学科学院医学与健康科技创新工程(2020-I2M-CoV19-006,2016-I2M-3-024)
中国医学科学院中央级公益性科研院所基本科研业务费专项资金(2018PT32016)
四川省国际科技创新合作/港澳台科技创新合作项目(2020YFH0024)。
关键词
输血相关
红细胞同种抗体
易感因素
transfusion-associated
RBC alloantibody
susceptibility factor
