摘要
目的分析影响使用静脉自控镇痛泵的妇科患者术后发生恶心呕吐的相关因素,为临床减少妇科患者术后恶心呕吐提供参考。方法回顾2018年01月至2018年12月1400例使用静脉自控镇痛泵妇科患者的术后麻醉查房记录,记录患者术后24h内是否出现恶心呕吐以及围术期相关信息。对影响患者术后发生恶心呕吐的相关因素进行统计学分析。结果使用静脉自控镇痛的妇科手术患者,术后24h内PONV发生率为28.5%。单因素分析显示:患者年龄、手术时长、术中止吐药物种类、PCIA泵止吐药物种类、止吐策略与术后恶心呕吐的发生有关(P<0.05)。多因素logistic回归分析显示:患者年龄、手术时长、止吐策略和PCIA泵舒芬太尼剂量是使用PCIA泵妇科手术患者术后24h内发生PONV的独立影响因素。结论对于术后使用PCIA泵的妇科患者,年龄大于45岁、手术时长大于2h、不使用止吐药物均是术后发生PONV的独立危险因素,PCIA泵的舒芬太尼剂量与PONV发生率呈正相关。
OBJECTIVE To analyze the factors related to the occurrence of nausea and vomiting after surgery in gynecological patients using patient-controlled intravenous analgesia pumps,and to provide a reference for clinical reduction of postoperative nausea and vomiting in gynecological patients.METHODS The records of 1,400 gynecological patients who used patient-controlled intravenous analgesia pumps from January 2018 to December 2018 were reviewed,and whether the patients had nausea and vomiting within 24 hours after surgery and perioperative information were recorded.Statistical analysis was conducted on the related factors affecting postoperative nausea and vomiting.RESULTS For the patients undergoing gynecological surgery with patient-controlled intravenous analgesia pumps,the incidence of PONV within 24 hours after surgery was 28.5%.Univariate analysis showed that patients′age,duration of operation,types of antiemetic drug during operation,types of PCIA pump antiemetic drug,and antiemetic strategies were related to postoperative nausea and vomiting(P<0.05).Multivariate logistic regression analysis revealed that patients′age,duration of surgery,antiemetic strategies,and unit weight dose of sufentanil in PCIA pump were independent factors for PONV within 24 hours after gynecological surgery with the PCIA pumps.CONCLUSION For gynecological patients using PCIA pumps after surgery,elder than 45 years,surgery duration longer than 2 hours,and no antiemetic medication during the operation are risk factors that increase the incidence of postoperative PONV.The dose of sufentanil in PCIA pump is positively correlated with PONV incidence.
作者
许文言
魏晓霞
刘艳洁
郑晓春
XU Wen-yan;WEI Xiao-xia;LIU Yan-jie;ZHENG Xiao-chun(Department of Anesthesiology,Fujian Medical University Shenli Clinical Medical College,Fujian Provincial Hospital,Fuzhou 350001,China;Department of Pharmacy,Fujian Medical University Shenli Clinical Medical College,Fujian Provincial Hospital,Fuzhou 350001,China)
出处
《海峡药学》
2022年第1期158-162,共5页
Strait Pharmaceutical Journal
关键词
妇科
静脉自控镇痛
术后恶心呕吐
Gynecological Surgery
PCIA
Postoperative nausea and vomiting
