摘要
目的观察认知功能在急性一氧化碳(CO)中毒患者焦虑与日常生活能力间的中介效应。方法采用便利抽样法选取安徽省阜阳市第二人民医院2018年1月至2021年1月收治的100例CO中毒患者作为研究对象。于患者脱离生命危险后,采用蒙特利尔认知评估量表(MoCA)评估患者认知功能,采用焦虑自评量表(SAS)评估患者焦虑程度,采用日常生活能力量表(ADL)评估患者日常生活能力,初步经Pearson相关性分析检验认知功能、焦虑与日常生活能力的关系后,采用中介效应检验程序检验认知功能在焦虑与日常生活能力间的中介效应。结果CO中毒患者SAS评分为(64.75±5.61)分,ADL评分为(36.38±5.19)分,MoCA评分为(24.57±3.32)分。Pearson直线相关性分析显示,CO中毒患者SAS评分与ADL及MoCA评分呈负相关(r=-0.321、-0.440,P<0.001);ADL评分与MoCA评分呈正相关(r=0.459,P<0.001)。采用方程Y=cX+e_(1)考察焦虑对日常生活能力的影响,得出回归效应显著;采用方程M=AX+e_(2)考察焦虑对认知功能的影响,得出回归效应显著;采用方程Y=c’X+bM+e_(3)考察认知功能在焦虑与日常生活能力间的中介效应,得出回归效应显著,为完全中介效应模型。结论认知功能在CO中毒患者焦虑与日常生活能力间发挥完全中介效应。
Objective To observe the mediating effect of cognitive function between anxiety and daily living ability in patients with acute carbon monoxide(CO)poisoning.Methods The convenience sampling method was used to select 100 patients with CO poisoning admitted to NO.2 People’s Hospital of Fuyang City from January 2018 to January 2021 as the research objects.After the patient was out of life-threatening,the Montreal cognitive assessment scale(MoCA)was used to assess the patient’s cognitive function,the self-rating anxiety scale(SAS)was used to assess the patient’s anxiety,and the daily life ability scale(ADL)was used to assess the daily life ability of the patient.After preliminary Pearson correlation analysis was used to test the relationship between cognitive function,anxiety,and daily life ability,the mediation effect test procedure was used to test the mediating effect of cognitive function between anxiety and daily life ability.Results The SAS score of patients with CO poisoning was(64.75±5.61)points,the ADL score was(36.38±5.19)points,and the MoCA score was(24.57±3.32)points.Pearson linear correlation analysis showed that SAS scores of patients with CO poisoning were negatively correlated with ADL scores and MoCA scores(r=-0.321,-0.440,P<0.001);ADL scores were positively correlated with MoCA scores(r=0.459,P<0.001).Using the equation Y=cX+e_(1) to investigate the influence of anxiety on the ability of daily living,it was concluded that the regression effect was significant;using the equation M=AX+e_(2) to investigate the impact of anxiety on cognitive function,it was concluded that the regression effect was significant;the equation Y=c’X+bM+e_(3) was used to investigate the mediating effect of cognitive function between anxiety and daily living ability,and it was concluded that the regression effect was significant,which was a complete mediating effect model.Conclusion Cognitive function plays a completely mediating effect between anxiety and daily living ability in patients with CO poisoning.
作者
汪莉萍
黄敏
杜丽娟
王梅
WANG Liping;HUANG Min;DU Lijuan;WANG Mei(Department of Emergency,NO.2 People’s Hospital of Fuyang City,Anhui Province,Fuyang236000,China;Department of Nursing,NO.2 People’s Hospital of Fuyang City,Anhui Province,Fuyang236000,China;the First Department of Liver,NO.2 People’s Hospital of Fuyang City,Anhui Province,Fuyang236000,China)
出处
《中国医药导报》
CAS
2022年第4期194-197,共4页
China Medical Herald
关键词
一氧化碳
中毒
认知功能
焦虑
日常生活能力
Carbon monoxide
Poisoning
Cognitive function
Anxiety
Ability of daily living
