摘要
T2DM是常见慢性代谢性疾病,给患者和社会带来沉重负担。控制餐后血糖(PPG),改善Ins分泌在T2DM患者的血糖管理中处于重要地位。二肽基肽酶4抑制剂沙格列汀可有效控制T2DM患者PPG,不良反应少,患者耐受良好。本文对T2DM患者PPG的临床意义、PPG升高机制、沙格列汀控制PPG的优势进行综述,旨在为临床治疗T2DM提供依据。
Type 2 diabetes mellitus(T2 DM)is a common chronic metabolic disease,which brings heavy burden to patients and society.Controlling postprandial blood glucose(PPG)and improving insulin secretion play an important role in blood glucose management of T2 DM patients.Dipeptidyl peptidase 4(DPP-4)inhibitor Saxagliptin can effectively control PPG in patients with T2 DM,with less adverse reactions and well tolerated.This article reviews the clinical significance of PPG,the mechanism of increasing PPG in patients with T2 DM,and the advantages of Saxagliptin in controlling PPG,in order to provide the basis for clinical treatment of T2 DM.
作者
王川
严励
WANG Chuan;YAN Li(Department of Endocrinology,Sun Yat-sen Memorial Hospital,Sun Yat-Sen University,Guangzhou 510120,China)
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2022年第2期147-150,共4页
Chinese Journal of Diabetes
关键词
二肽基肽酶4抑制剂
沙格列汀
糖尿病
2型
餐后血糖
Dipeptidyl peptidase 4 inhibitor
Saxagliptin
Diabetes mellitus
type 2
Postprandial glucose
