摘要
目的分析子宫内膜异位症(EM)相关不孕患者合并子宫内膜息肉(EP)的高危因素。方法选取107例因不孕症接受宫腹腔镜联合手术,且经腹腔镜检查及术后病理证实为EM患者,根据宫腔镜检查及术后病理结果,将患者是否合并EP分为EP组(60例)与非EP组(47例)。研究两组临床资料,探索EM不孕患者合并EP的高危因素。结果107例EM不孕患者中EP的发生率为56.1%。单因素分析显示:EP组年龄均值低于非EP组(P<0.05),EP组年龄≤36.5岁比例、子宫内膜厚度均值、子宫内膜厚度≥10.0 mm比例及原发性不孕比例均高于非EP组,差异有统计学意义(P<0.05),不同病理类型EM患者EP发生率比较,差异无统计学意义(P>0.05)。多因素二分类Logistic回归分析显示:发病年龄≤36.5岁(OR=5.409,95%CI 1.446,20.235,P<0.05)、子宫内膜厚度≥10.0 mm(OR=28.035,95%CI 7.152,109.891,P<0.01)是EM合并EP的独立危险因素,而原发性不孕(OR=1.033,95%CI 0.357,2.990,P>0.05)不是EM合并EP的独立危险因素。结论EM患者合并EP的比例较高,建议临床上对EM相关不孕患者行宫腹腔镜检查,尤其是年龄≤36.5岁、子宫内膜厚度≥10.0 mm的EM不孕患者,达到对EP进行早期诊治的目的,以期提高患者的妊娠率。
Objective To analyze the high risk factors of endometrial polyps in patients with endometriosis-related infertility.Methods 107 patients who underwent hysteroscopy combined with hysteroscopy for infertility and were confirmed as EM by laparoscopy and postoperative pathology were selected.According to hysteroscopy and postoperative pathological results,the patients with or without EP were divided into EP group(60 cases)and non-EP group(47 cases).The clinical data of the two groups were studied,and the risk factors of EP complicated with EM were explored.Results The incidence of EP in 107 EM infertile patients was 56.1%.The results of univariate analysis showed that the average age of EP group was lower than that of non-EP group(P<0.05),the proportion of age≤36.5 years,the average endometrial thickness,the proportion of endometrial thickness≥10.0mm and the proportion of primary infertility in EP group were higher than those in non-EP group(P<0.05),and there was no signifificant difference in the incidence of EP among different pathological types of EM patients(P>0.05).Multivariate Logistic regression analysis showed that onset age≤36.5 years(OR=5.409,95%CI 1.446,20.235,P<0.05)and endometrial thickness≥10.0 mm(OR=28.035,95%CI 7.152,109.891,P<0.01)were independent risk factors for EM complicated with EP,while primary infertility(OR=1.033,95%CI 0.357,2.990,P>0.05)was not an independent risk factor for EM complicated with EP.Conclusion The proportion of patients with EM complicated with EP is high.It is suggested that the patients with EM-related infertility should be clinically examined by hysteroscopy and laparoscopy,especially those with EM infertility of age≤36.5 years and endometrial thickness≥10.0 mm,so as to achieve the purpose of early diagnosis and treatment of EP and improve the pregnancy rate of patients.
作者
李文文
程玲慧
庞秋实
Li Wenwen;Cheng Linghui;Pang Qiushi(Department of Obstetrics and Gynecology,The First Affiffiffi liated Hospital of Anhui Medical University,Hefei 230022,China)
出处
《实用妇科内分泌电子杂志》
2022年第2期8-12,共5页
Electronic Journal of Practical Gynecological Endocrinology
