摘要
为了扩大大豆分离蛋白(SPI)纤维冷凝胶的潜在使用范围,通过体外缓释模型,探究SPI纤维冷凝胶对核黄素的控释效果。结果表明,SPI在pH 2.0下加热20 h后形成纳米纤维,导致Th T荧光、ζ-电位上升,表观粘度、稠度系数提高。将pH调至8.0后加入CaCl_(2)制得的冷凝胶对核黄素具有荷载及控制释放效果。与传统的SPI凝胶相比,这种纤维冷凝胶可以在较低的蛋白浓度下形成凝胶网络,可以用作核黄素的包封体,在食品科学、药物输送等领域具有广阔的应用前景。
In order to expand the potential uses of soy protein isolate(SPI)nanofibrils,the controlled release of SPI fibril cold-set gel was studied using riboflavin as a model drug under gastric and intestinal conditions.SPI had ability to assembly into fibrils at pH 2.0.Thioflavin T fluorescence,ζ-potential,apparent viscosity and consistency coefficient increased.Then,the pH of SPI fibril solution was adjusted to 8.0 and cold-set gel was formed by adding CaCl_(2).The in vitro release study of riboflavin showed a sustained release effect.Comparing with the conventional gel,SPI fibril cold-set gel could form at much lower concentrations and could be considered as a promising carrier for riboflavin.Therefore,SPI fibril cold-set gel could offer promising applications in food industry and drug delivery.
作者
关琛
李萌
李宁
周航庆
张建红
李琳
Guan Chen;Li Meng;Li Ning;Zhou Hangqing;Zhang Jianhong;Li Lin(College of Food Science,Heilongjiang Bayi Agricultural University,Daqing 163319;College of Food Science,Northeast Agricultural University)
出处
《黑龙江八一农垦大学学报》
2022年第1期72-78,共7页
journal of heilongjiang bayi agricultural university
基金
黑龙江省大学生创新创业训练计划项目(202010223137)。
关键词
大豆蛋白
纳米纤维
冷凝胶
缓释
soy protein
nanofibril
cold-set gel
controlled-release
