摘要
目的观察基于中医神明理论的穴位按摩结合常规认知康复训练对卒中后认知障碍患者认知功能、日常生活能力及血浆β淀粉样蛋白1-42(Aβ;)水平的影响。方法将66例卒中后认知障碍患者随机分为对照组和治疗组,每组33例。对照组采用常规认知康复训练,治疗组在对照组基础上加用基于中医神明理论的穴位按摩。两组疗程均为12周,观察蒙特利尔认知评估量表(Mo CA)、日常生活能力(ADL)评分和血浆Aβ;水平的变化情况。结果治疗前后组内比较,两组Mo CA评分值升高(P<0.05),ADL评分值、血浆Aβ;水平降低(P<0.05);组间治疗后比较,治疗组Mo CA评分高于对照组(P<0.05),血浆Aβ;水平低于对照组(P<0.05),ADL评分差异无统计学意义(P>0.05)。结论与单纯采用认知康复训练相比,联合使用基于中医神明理论的穴位按摩治疗卒中后认知障碍疗效满意,能更好地改善患者的认知功能,提高日常生活能力,降低血浆Aβ;水平。
Objective conventional cognitive rehabilitation training on cognitive function,activities of daily living and plasma concentrations of β-amyloid 1-42(Aβ;)in patients with post-stroke cognitive impairment.Methods control group(n=33)and a treatment group(n=33). The control group was administered with conventional cognitive rehabilitation training,and the treatment group was additionally administered with TCM Shen-Ming theory-based acupressure besides the treatment measures of the control group. The course of treatment of the two groups lasted 12 weeks,and the changes of Montreal Cognitive Assessment(MoCA)score,activities of daily living(ADLs)scale score and plasma concentrations of Aβ;were observed and compared.Results after treatment,MoCA scores increased(P<0.05)and ADL scores and the plasma concentrations of Aβ;decreased(P<0.05)in both groups.According to the inter-group comparison after treatment,MoCA score was higher in the treatment group than that in the control group(P<0.05),the plasma concentrations of Aβ;in the treatment group were lower than the concentrations in the control group(P<0.05),and there was no significant difference in ADL score between two groups(P>0.05).ConclusionCompared with the single use of cognitive rehabilitation training,the combined use of TCM Shen-Ming theory-based acupressure and cognitive rehabilitation training has achieved satisfactory results in treating post-stroke cognitive impairment,which can better improve patients’ cognitive function,facilitate activities of daily living and lower plasma concentrations of Aβ;.
作者
王健
金蕾
汪六运
王宁宁
高洁
张辉
WANG Jian;JIN Lei;WANGLiuyun;WANG Ningning;GAO Jie;ZHANG Hui(School of Rehabilitation Science,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Department of Traditional Chinese Medicine,Shanghai Hudong Hospital,Shanghai 200129,China;Department of Rehabilitation,Shanghai Hudong Hospital,Shanghai 200129,China)
出处
《上海中医药杂志》
2022年第1期71-74,共4页
Shanghai Journal of Traditional Chinese Medicine
基金
上海市卫计委面上项目(201840228)。
关键词
卒中后认知障碍
认知功能
穴位按摩
β淀粉样蛋白1-42
神明理论
中西医结合疗法
post-stroke cognitive impairment
cognitive function
acupressure
β-amyloid 1-42
Shen-Ming theory
integrated traditional Chinese and western medicine therapy
