摘要
目的探讨耳穴埋籽联合营养支持用于晚期肺癌相关性厌食患者的效果。方法选取2017年1月至2020年7月杭州市中医院丁桥院区呼吸科门诊或住院就诊的晚期肺癌相关性厌食患者88例,随机分为两组,每组各44例。单用组予单纯营养支持治疗,联用组在单用组基础上加耳穴埋籽治疗,两组均连用12周。观察并比较两组治疗前后营养状况指标[血清血红蛋白(HGB)、白蛋白(ALB)和转铁蛋白(TRF)]及体力状况指标(卡氏评分)的变化,并评估其临床效果。结果治疗12周后,单用组及联用组血清HGB、ALB和TRF水平分别为[(118.24±14.08)分、(129.25±14.24)分];[(30.05±4.81)分、(34.01±3.58)分];[(167.72±24.09)分、(174.75±29.14)分],均较治疗前[(103.55±12.21)分、(102.97±10.17)分;(27.90±3.34)分;(27.81±3.15)分;(154.41±20.42)分、(152.82±21.62)分]明显上升(P<0.05或P<0.01),且治疗后联用组上升幅度较单用组更明显(P<0.05);联用组、单用组卡氏功能评分[(65.07±9.72)分、(59.25±9.07)分]较前[(52.16±9.41)分、(51.87±8.75)分]明显上升(P<0.05或P<0.01),且联用组上升幅度较单用组更显著(P<0.05);同时联用组患者临床总有效率(95.46%)明显优于单用组(81.82%)(χ^(2)=4.060,P<0.05)。结论耳穴埋籽与营养支持联合治疗晚期肺癌相关性厌食患者的效果确切,能明显改善患者的营养状况,提高体力状况。
Objective To explore the efficacy of auricular points plaster therapy combined with nutritional support for patients with anorexia associated with advanced lung cancer.Methods A total of 88 patients with anorexia associated with advanced lung cancer admitted to the clinic of respiratory department or hospitalized of Dingqiao Branch of Hangzhou Hospital of Traditional Chinese Medicine from January 2019 to July 2020 were selected and randomly divided into the single treatment group(n=44)and the combined treatment group(n=44).The single treatment group was given simple nutritional support,while the combined group was treated with auricular points plaster therapy on the basis of the single treatment group.The two groups were continuously treated for 12 weeks.The changes of nutritional status indices[serum hemoglobin(HGB),albumin(ALB)and transferrin(TRF)]and physical status indices[Karnofsky score]before and after treatment were observed and compared between the two groups,and their clinical efficacies were evaluated.Results After 12 weeks of treatment,The single treatment group and the combined treatment group serum HGB,ALB and TRF levels in the two groups were[(118.24±14.08)points,(129.25±14.24)points,(30.05±4.81)points,(34.01±3.58)points,(167.72±24.09)points and(174.75±29.14)points],which were obviously higher than[(103.55±12.21)points,(102.97±10.17)points,(27.90±3.34)points,(27.81±3.15)points,(154.41±20.42)points and(152.82±21.62)points]before treatment(P<0.05 or P<0.01).And after treatment,the increase rate of the combined group was more significant than that of the single treatment group(P<0.05).the Karnofsky function score of the combined treatment group and the single treatment group were[(65.07±9.72)points and(59.25±9.07)points],which were significantly higher than[(52.16±9.41)points and(51.87±8.75)points]before treatment(P<0.05 or P<0.01).And the increase range of the combined treatment group was more obvious than that of the single treatment group(P<0.05).At the same time,the total clinical
作者
罗佳
潘俊杰
LUO Jia;PAN Junjie(Department of Respiratory,Dingqiao Branch of Hangzhou Hospital of Traditional Chinese Medicine(Hangzhou Dingqiao Hospital),Hangzhou310000,China)
出处
《中国现代医生》
2022年第2期127-130,共4页
China Modern Doctor
基金
浙江省中医药科技计划项目(2020ZQ039)。
关键词
晚期肺癌相关性厌食
营养干预
耳穴埋籽
营养状况
体力状况
Anorexia associated with advanced lung cancer
Nutrition intervention
Auricular points plaster therapy
Nutritional status
Physical strength status