摘要
目的探究静脉注射地佐辛超前镇痛在腹腔镜阑尾切除术患者中的应用效果。方法利用随机数字表法将70例拟进行腹腔镜阑尾切除术的阑尾炎患者分为观察组与对照组,每组35例。观察组给予全麻+静脉注射地佐辛超前镇痛,对照组给予全麻+等剂量生理盐水。比较两组的术前、术中及术后相关指标。结果观察组切皮时、进行阑尾牵拉时的心率及平均动脉压高于对照组(P<0.05)。观察组术后恶心、呕吐、烦躁不安的发生率低于对照组(P<0.05)。观察组的术后24 h VAS评分显著低于对照组,睁眼时间、拔管时间、呼吸恢复时间显著短于对照组(P<0.05)。术后3 h,两组的血清NE、E水平均较术前升高,但观察组低于对照组(P<0.05)。结论给予腹腔镜阑尾炎切除术患者地佐辛静脉注射超前镇痛,有利于维持患者心率、平均动脉压的稳定,降低不良反应发生率,减轻术后疼痛及应激反应。
Objective To explore the application effects of intravenous injection of dizocine for preemptive analgesia in patients undergoing laparoscopic appendectomy. Methods Seventy appendicitis patients who planned to undergo laparoscopic appendectomy were divided into observation group and control group according to random number table method, with 35 cases in each group. The observation group was given general anesthesia + intravenous injection of dizocine for preemptive analgesia, and the control group was given general anesthesia + equal dose normal saline.The preoperative, intraoperative and postoperative indexes of the two groups were compared. Results The heart rate and mean arterial pressure in the observation gro up were higher than those in the control group at skin cutting and appendix traction(P <0.05). The incidences of postoperative nausea, vomiting and irritability in the observation group were lower than those in the control group(P<0.05). The VAS score at 24 h after operation in the observation group was significantly lower than that in the control group, and the eye opening time, extubation time and respiratory recovery time was significantly shorter than that in the control group(P <0.05). At 3 h after operation, the levels of serum NE and E in both groups were higher than those before operation, but those of the observation group were lower than the control group(P <0.05). Conclusion Intravenous injection of dezocine for preemptive analgesia applied in patients undergoing laparoscopic appendectomy is helpful to maintain the stability of heart rate and mean arterial pressure,decrease the incidence of adverse reactions, and reduce postoperative pain and stress response.
作者
程丽红
曹小飞
骆善志
CHENG Lihong;CAO Xiaofei;LUO Shanzhi(Anesthesiology Department,Shuyang Zhongxing Hospital,Suqian 223600;Anesthesiology Department,Jiangsu Provincial People's Hospital,Nanjing 210029,China)
出处
《临床医学研究与实践》
2022年第4期96-98,共3页
Clinical Research and Practice
关键词
阑尾切除术
地佐辛
超前镇痛
心率
平均动脉压
appendectomy
dizocine
preemptive analgesia
heart rate
mean arterial pressure
