摘要
目的分析成都市金牛区2013-2020年新报告人类免疫缺陷病毒(HIV)感染者/艾滋病(AIDS)患者(简称HIV/AIDS病例)的首次CD4^(+)T淋巴细胞(简称CD4细胞)检测结果,为制订针对性防控措施提供依据。方法收集该区2013-2020年新报告HIV/AIDS病例资料,对首次CD4细胞检测结果及影响因素进行分析。结果该区2013-2020年新报告HIV/AIDS病例中接受首次CD4细胞检测1910例(90.35%),首次CD4细胞计数<200个/微升583例(30.52%),其中14 d内接受检测1135例(59.42%)。2013-2020年新报告HIV/AIDS病例首次CD4细胞检测比例无明显上升趋势(χ_(趋势)^(2)=0.240,P=0.624),检测结果的分布差异有统计学意义(χ^(2)=37.692,P=0.014),CD4细胞计数<350个/微升占比大;2013-2020年首次CD4细胞检测及时性的差异有统计学意义(χ^(2)=139.270,P<0.001),14 d内接受检测占比最大,且从2013年的52.27%上升至2020年的69.35%(χ_(趋势)^(2)=39.911,P<0.001)。多因素Logistic回归分析显示,男性、年龄越大、户籍为本区、婚姻状况为已婚有配偶的HIV/AIDS病例发生首次CD4细胞计数<200个/微升的比例更高;年龄越大、样本来源于咨询检测,更易及时检测CD4细胞。结论近年成都市金牛区新报告HIV/AIDS病例的首次CD4细胞检测比例无明显上升趋势,中度和重度免疫缺陷占比高,首次CD4细胞检测及时性提高。性别、年龄、户籍、婚姻状况、样本来源对首次CD4细胞检测结果均有影响。
Objective To analyze the results of the fist time CD4^(+)T lymphocyte(CD4)test among newly reported HIV/AIDS cases in Jinniu District during 2013-2020 to provide a basis for the targeted prevention and control measures.Methods The data of newly reported HIV/AIDS cases in Jinniu District during 2013-2020 were collected,and the situation of the first time CD4 test and influencing factors were analyzed.Results Among the newly reported cases of HIV/AIDS in this district during 2013-2020,1910 cases(90.35%)received the first time CD4 test,the CD4 count<200 cells/μL was in 583 cases(30.52%),receiving the CD4 test within 14 d was in 1135 cases(59.42%).The proportion of the first time CD4 test in the newly reported HIV/AIDS cases during 2013-2020 had no obvious increasing trend(χ_(trend)^(2)=0.240,P=0.624),but there was statistical difference in the test results constituents(χ^(2)=37.692,P=0.014),the proportion of CD4 count<350 cells/μL was large;there was statistical difference in the timeliness receiving the first time CD4 test during 2013-2020(χ^(2)=139.270,P<0.001),the proportion receiving the CD4 test within 14 d was maximal,moreover the proportion was increased from 52.27%in 2013 to 69.35%in 2020(χ_(trend)^(2)=39.911,P<0.001).The multivariate Logistic regression analysis showed that the proportion of CD4<200 cells/μL in the first time test among the HIV/AIDS cases of male,older age,registered residence in this district and marital status with spouse was higher,and those with older age and the sample derived from the consulting were easier to detect the CD4 cells timely.Conclusion In recent years,the proportion of the first time CD4 test in newly reported HIV/AIDS cases in Jinniu District shows no obvious rising trend,the proportion of moderate and severe immunodeficiency is relatively high and the timeliness of the first time CD4 test is improved.Gender,age,registered residence,marital status and sample sources have the impact on the results of the first time CD4 test.
作者
孙敏
张冉
罗叶
熊洋
傅育嵩
SUN Min;ZHANG Ran;LUO Ye;XIONG Yang;FU Yusong(Third Department of Disease Control,Jinniu District Center for Disease Control and Prevention,Chengdu,Sichuan 610037,China)
出处
《国际检验医学杂志》
CAS
2022年第4期479-484,490,共7页
International Journal of Laboratory Medicine
