摘要
组织再生是现代医学的热点话题,科学家们尝试通过各种支架来提供组织细胞生长平台,以达到组织再生的目的,但在实际应用中常常因为支架植入后无法通过体外无创检查精准监控组织再生情况、支架难降解等问题而难以进行临床试验。碳点是一类尺寸小于10 nm的球形纳米材料,近年来由于其生物相容性良好、水溶性和稳定性优异等特质而备受关注。简单介绍了碳点的制备方法、生物学性质及其在组织再生支架中的作用。
Tissue regeneration is a hot spot in modern medicine.Scientists try to provide a platform for cell growth through various scaffolds to attain the purpose of tissue regeneration.However,it is often difficult to conduct clinical trials in the terms of the problems such as the inability to accurately monitor tissue regeneration through non-invasive in vitro inspections after scaffold implantation,and the difficulty of degradation of the scaffold.The carbon dots are a class of spherical nanomaterials with a size of less than 10 nm,which have become the focus of research in recent years,due to their good biocompatibility,excellent water solubility and stability.In this article,we briefly introduce the preparation methods,biological properties,and applications in tissue regeneration scaffolds of carbon dots.
作者
李泽华
谢元栋
詹骆宁
胡玲
刘晓莉
李毅
LI Zehua;XIE Yuandong;ZHAN Luoning;HU Ling;LIU Xiaoli;LI Yi(Department of Pediatric Dentistry,Hospital of Stomatology,Jilin University,Changchun 130021,China;Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling,Changchun 130021,China)
出处
《化学与生物工程》
CAS
2022年第2期6-9,共4页
Chemistry & Bioengineering
基金
吉林省科学技术厅自然科学基金项目(2020021409JC)
吉林省财政厅科技项目(JCSZ20200304-6)。
关键词
组织再生
支架
碳点
tissue regeneration
scaffold
carbon dot
