摘要
目的观察益气通络清热膏方治疗老年2型糖尿病动脉粥样硬化患者的临床疗效。方法回顾性分析2019年6月—2021年6月在黄石市中医医院住院的老年2型糖尿病动脉粥样硬化患者80例,按数字表法随机分为观察组(n=40)与对照组(n=40)。对照组给予常规西药口服治疗,观察组给予益气通络清热膏方联合常规西药口服治疗。治疗前与治疗后4个月,观察并比较2组双侧颈动脉、腘动脉和足背动脉血管内径(blood vessel diameter,BVD)、峰值流速(peak flow velocity,PV)、血流量(BF)以及总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、纤维蛋白原(Fg)和踝肱指数(ABI)的变化;比较2组治疗后总有效率、不良反应和患者生活质量维度评分。结果治疗4个月后,2组颈总动脉、腘动脉和足背动脉的BVD、PV、BF值和HDL-C水平和ABI值均高于同组治疗前(P<0.05),TC、TG、LDL-C水平和Fg值均显著低于同组治疗前(P<0.05);2组生理、心理/精神、社会关系和治疗维度评分均低于同组治疗前(P<0.05)。观察组治疗后的上述指标的改善幅度均大于对照组。观察组总有效率高于对照组(P<0.05),而不良反应发生率低于比对照组(P<0.05)。结论益气通络清热膏方治疗老年2型糖尿病动脉粥样硬化患者疗效明显,不良反应较少,同时也使患者生活质量提高,值得在临床上推广应用。
Objective To observe the clinical effect of Yiqi Tongluo Qingre cream in the treatment of elderly patients with type2 diabetes and atherosclerosis. Methods 80 elderly patients with type2 diabetes and atherosclerosis who were hospitalized in Traditional Chinese Medicine Hospital of Huangshi City from June2019 to June2021 were retrospective analyzed. According to the digital table method,they were randomly divided into observation group(n= 40)and control group(n= 40). The control group was treated with conventional western medicine,and the observation group was treated with Yiqi Tongluo Qingre cream combined with conventional western medicine. Before treatment and4 months after treatment,the blood vessel diameter(BVD),peak flow velocity(PV)and blood flow(BF)of bilateral common carotid artery,popliteal artery and dorsalis pedis artery,as well as the levels of total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C),plasma fibrinogen(Fg)and ankle brachial index(ABI)were observed and compared between the two groups. The total effective rate,adverse reactions and total scores of life quality of the patients were compared between the two groups after treatment. Results After4 months of treatment,the values of BVD,PV,BF and ABI and HDL-C level of common carotid artery,popliteal artery and dorsalis pedis artery of the two groups were higher than those of the same group before treatment(P< 0.05),and the levels of TC,TG,LDL-C and Fg were significantly lower than those of the same group before treatment(P< 0.05);the scores of physiology,psychology/spirit,social relationship and treatment dimensions of the two groups were lower than those of the same group before treatment(P< 0.05). The improvement range of above indexes of the observation group after treatment was greater than thatof the control group(P< 0.05). The total effective rate of the observation group was higher than that of the control group(P< 0.05),and the incidence of adverse reactions was lowe
作者
刘慧君
陈锋
范冠杰
杨凤明
Liu Huijun;Chen Feng;Fan Guanjie;Yang Fengming(Department of Endocrinology,Traditional Chinese Medicine Hospital of Huangshi City,Huangshi,Hubei,435000,P.R.China;Department of Endocrinology,Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine,Guangzhou,Guangdong,510120,P.R.China)
出处
《老年医学与保健》
CAS
2022年第1期148-153,共6页
Geriatrics & Health Care
基金
2016~2017年湖北省卫计委中西医结合科研一般项目(鄂卫生计生通[2017]20号)。
关键词
老年
2型糖尿病
动脉粥样硬化
益气通络清热
膏方
elderly
type 2 diabetes
mellitus
atherosclerosis
Yiqi Tongluo Qingre
cream formula
