摘要
鼻咽癌是我国为数不多的有国际话语权的疾病,百年的发展已使5年生存率从20%提高到85%以上,10年生存接近70%,标志着鼻咽癌进入“长生存”新时代。尽管如此,目前仍有一部分患者会出现复发和转移,无法彻底根除。对于二次放疗患者,生存质量显著下降,攻克鼻咽癌治疗的最后一公里成为众多医学家的期望。随着影像技术的不断进步、放疗设备的更新换代、新型药物的问世以及人工智能的广泛运用,寻求“代价最小、疗效最佳、临床最优化”的诊疗方案是鼻咽癌新时代面临的新挑战,突破在于精准诊疗思维的建立,包括早期筛查、精准分期、精准靶区画像、复发转移性鼻咽癌优化处理、联合治疗模式选择等。
Nasopharyngeal cancer is one of the few medical fields in whic h China is internationally leading.The last 10 decades saw a 5-year survival rate increasing from 20% to more than 85%,and a 10-year survival rateapproaching 70%,indicating that nasopharyngeal carcinoma has entered a new era of‘long-term survival’.Nevertheless,some patients still suffered from recurrence and metastasisafter radical treatment.For patients receivingreirradiation,quality of life decreased significantly.Conquering the long-pendingproblems in nasopharyngeal cancer treatmenthas become the expectation of many distinguishing physicians.With the rapid development of imaging technology,the upgradesin radiotherapy equipment,the advent of new drugs and the widespread application of artificial intelligence,seeking a diagnosis and treatment scheme of‘minimum cost,best curative effect and optimized clinical practice’is a new challenge for us in this era.The breakthroughsrely on the establishment ofan accurate medical thinking,including early screening,accurate staging,precise target delineation,optimal management of recurrent and metastatic cases,and appropriate comprehensive treatment.
作者
冯梅
王卫东
郎锦义
Feng Mei;Wang Weidong;Lang Jinyi(Department of Oncology,the Third People’s Hospital of Sichuan Province,Chengdu 610100,Sichuan,China;Sichuan Key Lab of RadiationOncology,Sichuan Cancer Hospital&Institute,SichuanCancer Center,School of Medicine,University of Electronic Science and Technology of China,Chengdu 610041,Sichuan,China)
出处
《肿瘤预防与治疗》
2022年第1期1-6,共6页
Journal of Cancer Control And Treatment
基金
四川省科技计划项目(编号:22ZDYF0775、2020YJ0446)。
关键词
鼻咽癌
现代诊疗
长生存
高效低毒
Nasopharyngeal carcinoma
Modern diagnosis and treatment
Long-term survival
High efficiency and low toxicity
