摘要
Papillary thyroid carcinoma(PTC)is the most common type(accounting for over 80%)of thyroid cancer.[1]Although PTC is a well-differentiated endocrine neoplasm,unfortunately,certain PTCs show malignant characteristics such as aggressiveness and metastasis;these characteristics contribute to a poor 5-year survival rate.[1]However,the fundamental molecular mechanism of extra-thyroid metastasis remains unclear.
基金
This study was supported by the grants from the Research Development Fund of The Second Hospital of Shandong University(No.11681808)
Jinan clinical medical science and technology innovation plan(No.202019194).