摘要
目的研究盐酸氨溴索治疗老年肺炎的效果。方法100例进行手术治疗的老年肺炎患者,根据双盲法分为对照组和研究组,各50例。对照组实施常规治疗,研究组在对照组基础上进行盐酸氨溴索治疗。比较两组患者肺功能、治疗时间、症状消失时间(止咳、退热、肺部啰音消失时间)、治疗效果、不良反应发生情况、治疗满意度。结果治疗后,研究组患者第1秒用力呼气容量占预计值百分比(FEV1%)、用力肺活量(FVC)、FEV1/FVC分别为(67.85±2.57)%、(2.97±0.34)L、(78.52±2.59)%,均高于对照组的(66.14±2.37)%、(2.52±0.57)L、(76.89±2.43)%,差异均具有统计学意义(P<0.05)。研究组患者止咳时间(5.39±1.29)d、退热时间(2.52±1.43)d、肺部啰音消失时间(3.78±1.51)d、治疗时间(5.09±1.82)d均短于对照组的(6.29±1.63)、(4.95±1.07)、(4.42±1.65)、(6.78±1.71)d,差异均具有统计学意义(P<0.05)。研究组治疗总有效率98.00%高于对照组的86.00%,差异具有统计学意义(P<0.05)。研究组不良反应发生率8.00%与对照组的6.00%比较,差异无统计学意义(P>0.05)。研究组对用药指导工作满意度96.00%高于对照组的84.00%,差异具有统计学意义(P<0.05)。研究组对治疗效果满意度98.00%高于对照组的86.00%,差异具有统计学意义(P<0.05)。结论老年肺炎患者予以盐酸氨溴索治疗能改善肺功能,提高治疗效果,加速病情好转,且该药物安全可靠,值得应用。
Objective To study the effect of ambroxol hydrochloride on treatment of senile pneumonia.Methods A total of 100 cases of senile pneumonia undergoing surgical treatment were divided into control group and research group according to the double-blind method,with 50 cases in each group.The control group received conventional treatment,and the research group received ambroxol hydrochloride treatment on this basis.Both groups were compared in terms of lung function,treatment time,symptom disappearance time(cough disappearance time,antipyretic time,pulmonary rales disappearance time),therapeutic effect,occurrence of adverse reactions,and treatment satisfaction.Results After treatment,the forced expiratory volume in the 1st second as a percentage of the predicted value(FEV1%),forced vital capacity(FVC),FEV1/FVC were(67.85±2.57)%,(2.97±0.34)L,and(78.52±2.59)%,which were higher than(66.14±2.37)%,(2.52±0.57)L,and(76.89±2.43)%of the control group,and the differences were statistically significant(P<0.05).The cough disappearance time(5.39±1.29)d,antipyretic time(2.52±1.43)d,pulmonary rales disappearance time(3.78±1.51)d,and treatment time(5.09±1.82)d of the research group were shorter than(6.29±1.63),(4.95±1.07),(4.42±1.65),and(6.78±1.71)d of the control group,and the differences were statistically significant(P<0.05).The total effective rate of treatment 98.00%of the research group was higher than 86.00%of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions was 8.00%in the research group and 6.00%in the control group,and the difference was not statistically significant(P>0.05).The satisfaction with medication guidance 96.00%in the research group was higher than 84.00%in the control group,and the difference was statistically significant(P<0.05).The satisfaction with the therapeutic effect 98.00%in the research group was higher than 86.00%in the control group,and the difference was statistically significant(P<0.05).Conclusion Ambroxol hydrochloride for el
作者
钟风芳
冯鑫
ZHONG Feng-fang;FENG Xin(Zhejiang Geriatric Care Hospital,Hangzhou 310015,China)
出处
《中国实用医药》
2022年第3期131-134,共4页
China Practical Medicine
关键词
盐酸氨溴索
老年肺炎
治疗效果
Ambroxol hydrochloride
Senile pneumonia
Therapeutic effect
