摘要
目的:探讨使用快速液体复苏疗法治疗小儿脓毒症休克的效果。方法:选取2020年1月至2021年1月期间枣庄矿业集团中心医院收治的60例脓毒症休克患儿作为研究对象。随机将这些患儿分为对照组和观察组。为对照组患儿使用传统的扩容疗法进行治疗,为观察组患儿使用快速液体复苏疗法进行治疗。然后观察两组患儿血清尿素氮的水平、血清肌酐的水平、尿量、补液量、住ICU的时间、治疗开始至循环恢复稳定的时间、血清乳酸的水平、血清乳酸清除率及发生并发症的情况。结果:治疗后,观察组患儿的尿量多于对照组患儿,其补液量少于对照组患儿,其住ICU的时间及治疗开始至循环恢复稳定的时间均短于对照组患儿,其并发症的发生率均低于对照组患儿,P<0.05。治疗后6 h,观察组患儿血清乳酸的水平低于对照组患儿,其血清乳酸清除率高于对照组患儿,P<0.05。结论:使用快速液体复苏疗法治疗小儿脓毒症休克可增加患儿的尿量,快速地使其循环恢复稳定,降低其血清乳酸的水平,提高其乳酸清除率,缩短其住ICU的时间,且补液量较少,其并发症的发生率较低。
Objective:To investigate the effect of rapid fluid resuscitation therapy on septic shock in children.Methods:A total of 60 children with septic shock treated in Central Hospital of Zaozhuang Mining Group from January 2020 to January 2021 were selected as the research objects.These children were randomly divided into control group and observation group.The control group was treated with traditional dilatation therapy,and the observation group was treated with rapid fluid resuscitation therapy.Then,the serum urea nitrogen level,serum creatinine level,urine volume,fluid volume,ICU stay time,the time from the beginning of treatment to the stabilization of circulation,serum lactic acid level,serum lactic acid clearance rate and the occurrence of complications in the two groups were observed.Results:After treatment,the urine volume of the observation group was more than that of the control group,the fluid volume was less than that of the control group,the ICU stay time and the time from the beginning of treatment to the stabilization of circulation were shorter than that of the control group,and the incidence of complications were lower than that of the control group,P<0.05.6 h after treatment,the level of serum lactic acid in the observation group was lower than that in the control group,and the serum lactic acid clearance rate was higher than that in the control group,P<0.05.Conclusion:Rapid fluid resuscitation therapy for septic shock in children can increase urine volume,rapidly stabilize circulation,reduce serum lactate level,improve lactate clearance rate,shorten ICU stay time,and reduce the amount of fluid replacement,and lower the incidence of complications.
作者
高炜
金培田
GAO Wei;JIN Peitian(Central Hospital of Zaozhuang Mining Group,Zaozhuang Shandong,277000)
关键词
快速液体复苏
小儿
脓毒症休克
rapid fluid resuscitation
Children
Septic shock
