摘要
目的:探究CKD-EPI公式对血液透析患者残余肾功能的适用性。方法:对收治的126例慢性肾脏病血液透析患者随机分组进行研究,分为MD组(MDRD公式组)与CK组(CKD-EPI公式组)两组,患者人数比例1∶1,采用酶法分别检测Scr、尿素氮(BUN)和cys-c,将结果分别代入两种公式进行计算,对结果进行统计学分析。结果:MD组rGFR高于CK组,差异有统计学意义(P<0.05)。MD组整体适应性较CK组低,差异有统计学意义(P<0.05)。MD组在rGFR≥60 ml/(min·1.73 m^(2))时精确度和准确性较CK组低,差异有统计学意义(P<0.05)。MD组在rGFR<60 ml/(min·1.73 m^(2))时精确度和准确度较CK组低,差异有统计学意义(P<0.05)。结论:CKD-EPI公式是一种新的评估方法,其评估的准确度及预测性均较强,对于残余肾功能具有较强的适用性。
Objective To explore the applicability of CKD-EPI formula for residual renal function in hemodialysis patients.Method 126 hemodialysis patients with chronic kidney disease were randomly divided into MD group(MDRD formula group)and CK group(CKD-EPI formula group)with a ratio of 1∶1,Scr,BUN and Cys-C were detected by enzyme method,and the results were put into the two formulas for calculation,and the results were statistically analyzed.Results The rGFR of MD group was higher than that of CK group,there was a difference between the two groups(P<0.05).The overall permeability of MD group was lower than that of CK group(P<0.05),when rGFR≥60 ml(min·1.73 m^(2)),the accuracy and accuracy of MD group were lower than those of CK group(P<0.05).When rGFR<60 ml/(min·1.73 m^(2)),the accuracy and accuracy of MD group was lower than those of CK group(P<0.05).Conclusion CKD-EPI formula is a new evaluation method,which has strong accuracy and predictability,and has strong applicability for residual renal function.
作者
欧阳秀梅
周巧云
利璟施
OUYANG Xiu-mei;ZHOU Qiao-yun;LI Jing-shi(Hemodialysis room,Shenzhen Seventh People′s Hospital,Shenzhen 518081,China)
出处
《吉林医学》
CAS
2022年第1期38-41,共4页
Jilin Medical Journal
