摘要
目的研究重复经颅磁刺激(rTMS)联合高压氧(HBO)对颅脑损伤后昏迷患者的促醒疗效。方法选取2019年1月至2020年8月于滨州医学院附属医院康复科住院的脑外伤后昏迷患者87例,按照随机数字表法分为对照组、HBO组及联合治疗组,每组29例。对照组采用药物和常规康复治疗,HBO组在对照组基础上加用HBO治疗,联合治疗组在HBO组基础上加用rTMS治疗,比较3组治疗前及治疗1个月后格拉斯哥昏迷量表(GCS)评分及改良国际昏迷恢复量表(CRS-R)评分。结果治疗前,3组GCS及CRS-R评分比较差异无统计学意义;治疗1个月后,HBO组及联合治疗组GCS及CRS-R评分均高于对照组,且联合治疗组高于HBO组,差异均有统计学意义(P<0.05)。结论 rTMS联合HBO治疗对颅脑损伤后昏迷患者的促醒具有协同作用,二者联合能更好地改善患者的昏迷状态,提高康复疗效。
Objective To observe the effect of repetitive transcranial magnetic stimulation(rTMS) with combined hyperbaric oxygen(HBO) on coma patients after traumatic brain injury. Methods 87 coma patients after traumatic brain injury in Rehabilitation Department of Binzhou Medical University Hospital from January 2019 to August 2020 were selected and they were divided into control group, HBO group and combined treatment group according to random number table method, with 29 cases in each group. The control group was treated with drugs and routine rehabilitation treatment, the HBO group was treated with HBO on the basis of the control group, and the combined treatment group was treated with rTMS on the basis of the HBO group. The scores of Glasgow coma scale(GCS) and modified International coma recovery scale revised(CRS-R) were compared before and 1 month after treatment among three groups. Results There was no significant difference in the GCS and CRS-R scores among the three groups before treatment. After treatment, the GCS and CRS-R scores in the HBO and combined treatment groups were both significantly higher than that of the control group, while the combined treatment group were significantly higher than that of the HBO group, the difference was significant(P<0.05). Conclusion rTMS combined with HBO has synergistic effect on coma patients after traumatic brain injury, so the combination of rTMS and HBO can better improve the coma status of patients and improve the rehabilitation effect.
作者
冯真真
王德强
王群
郭萌
刘夏
FENG Zhenzhen;WANG Deqiang;WANG Qun;GUO Meng;LIU Xia(Department of Rehabilitation Medicine,Binzhou Medical University Hospital,Binzhou,Shandong,256600,China)
出处
《当代医学》
2022年第5期31-34,共4页
Contemporary Medicine
关键词
重复经颅磁刺激
高压氧
昏迷
促醒
Repetitiive transcranial magnetic stimulation
Hyperbaric oxygen
Coma
Awakening
