摘要
目的:探讨冠心病伴发抑郁患者中医证候特征。方法:计算机检索中国知网、万方数据库、维普数据库从建库至2020年12月31日关于冠心病伴发抑郁流行病学调查、中医药辨治的临床观察或随机对照试验等文献,提取目标文献中关于冠心病伴发抑郁的中医证类及其症状、体征信息,运用Microsoft Excel软件建立中医证候特征数据库,对中医证类、证候要素、症状、体征等信息进行频数统计。结果:纳入目标文献46篇,共计3446例冠心病伴发抑郁患者,提取出20种中医证类,8个病性证素、5个病位证素、38个频率>3%的主要症状与体征。结论:3446名冠心病伴发抑郁患者主要5种中医证类为气滞血瘀证、痰瘀互结证、肝郁气滞证、心血瘀阻证、气虚血瘀证;病性证素主要为血瘀、气滞、痰浊、气虚、火;病位证素主要为肝、心、脾、胆、肾;主要症状为胸痛、胸闷、失眠多梦、心悸、胸胁胀满或妇女乳房胀痛、气短、乏力、口干、善太息等,病因病机为因情志不遂、饮食不节、年老体虚致“阳虚血瘀”,阻遏心脉,神失濡养,最终发展成为冠心病伴发抑郁疾病。
Objective:To explore the characteristics of TCM syndromes in patients suffering CHD and depression(CHDD).Methods:Clinical observation or randomized controlled trials(RCTs)on epidemiological investigation and TCM syndrome differentiation and treatment of CHDD were searched in CNKI,Wanfang and VIP from data establishment to December 31,2020 using computer,after extracting TCM syndrome,symptoms and body signs of CHDD in the targeted literature,Microsoft Excel software was used to establish database of TCM syndrome characteristics,to conduct frequency statistics of TCM syndrome,syndrome elements,symptoms,body signs and others.Results:A total of 3446 patients suffering CHDD were included in 46 target literatures,20 TCM syndromes were extracted,including eight disease syndrome elements,five disease location syndrome elements and 38 main symptoms and signs with a frequency of more than 3%.Conclusion:Five TCM syndromes of 3446 patients are Qi stagnation and blood stasis pattern,phlegm and blood stasis pattern,liver depression and Qi stagnation pattern,heart-blood stasis pattern,Qi deficiency and blood stasis pattern,disease syndrome elements are blood stasis,Qi depression,phlegm turbidity,Qi deficiency and fire;disease location syndrome elements contain liver,heart,spleen,gallbladder and kidney;the main symptoms are chest pain,chest tightness,insomnia and dreaminess,palpitation,distension of hypochondrium or breast tenderness,panting,dry mouth,frequent sighing and others,the cause and the pathogenesis are Yang deficiency and blood stasis,obstructing heart vessels and spirit losing nurturing induced by emotional upset,improper diet,aging and weakness,consequently,it develops into CHDD.
作者
雷舒扬
常兴
王丽颖
刘大胜
韩学杰
LEI Shuyang;CHANG Xing;WANG Liying;LIU Dasheng;HAN Xuejie(Institute of Clinical Basic Medicine of Traditional Chinese Medicine of CACMS,Beijing 100700,China;Guang'anmen Hospital of CACMS)
出处
《西部中医药》
2022年第1期63-68,共6页
Western Journal of Traditional Chinese Medicine
基金
国家自然科学基金(81904325)
国家中医药管理局(GZY-FJS-2017-60)。
关键词
冠心病伴发抑郁
双心疾病
证候
病因病机
阳虚血瘀
CHDD
bicardiac disease
syndrome
the cause and the pathogenesis
Yang deficiency and blood stasis
