摘要
钛及钛合金因其良好的生物相容性广泛应用于医学领域中。但钛表面的生物活性会随暴露时间的增加而逐渐下降,影响其最终的骨结合效能。作为一种有效的表面改性方法,紫外线光功能化技术不改变成品种植体的表面形貌,适合多数品牌的成品种植体表面处理。本文从紫外线光功能化技术对钛表面特性、细胞生物学行为、种植体骨结合的影响及临床应用现状等方面对紫外线光功能化技术的研究进展作一综述。目前研究表明,紫外线光功能化后的钛表面表现为超亲水性,钛表面的生物活性提高,从而加速和增强骨形成,获得更好更快的骨结合,提高种植手术的成功率,适合椅旁操作,是一种有潜力的椅旁临床新技术。
Excellent mechanical properties and biocompatibility resulted in titanium and titanium alloys being wide⁃ly used in the medical field.However,the biological activity of atitanium surface will gradually fade with increasing ex⁃posure time,which affects its final osseointegration.As an effective surface modification method,ultraviolet(UV)photo⁃functionalization does not change the surface morphology of implants and is a suitable surface treatment for many brands of implants.This article summarizes the research progress on the effect of UV photofunctionalization technology on the characteristics of titanium surfaces,biological activity and implant osseointegration,as well as its current clinical applications.Studies have shown that the superhydrophilicity of the titanium surface and improved biological activity en⁃dowed by UV photofunctionalization can accelerate and enhance bone formation,resulting in a higher success rate of im⁃plant surgery.Therefore,UV photofunctionalization has great potential for clinical chairside applications.
作者
张华英
赵雨薇
于海洋
ZHANG Huaying;ZHAO Yuwei;YU Haiyang(State Key Laboratory of Oral Diseases&Nationgal Clini-cal Research Center for Oral Disease&Department of Prosthodontics,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China)
出处
《口腔疾病防治》
2022年第4期295-299,共5页
Journal of Prevention and Treatment for Stomatological Diseases
基金
国家重点研发计划项目(2016YFC1102704)
四川大学横向项目(19H0847)。
关键词
钛种植体
表面处理
椅旁操作
紫外线
光功能化
亲水性
碳氢化合物
生物活性
骨结合
titanium implant
surface modification
chairside operation
ultraviolet light
photofunctionaliza⁃tion
hydrophilic
hydrocarbon
biological activity
osseointegration
