摘要
目的:研究慢性乙型肝炎(CHB)患者行恩替卡韦治疗的效果。方法:选取长沙市第一医院2019年8月至2021年5月收治的80例CHB患者,采用"硬币分组法"分为对照组(40例,阿德福韦治疗)和观察组(40例,恩替卡韦治疗),比较两组患者的疗效。结果:两组患者用药前的肝功能、用药后的不良反应发生率比较,差异均无统计学意义(P>0.05);与对照组患者比较,观察组用药后的谷丙转氨酶(ALT)、谷草转氨酶(AST)及总胆红素(TBIL)均更低,总有效率更高,差异均具有统计学意义(P<0.05)。结论:恩替卡韦治疗CHB患者的疗效好,可改善其肝功能。
Objective To study the effect of entecavir in patients with chronic hepatitis B (CHB).Methods A total of 80 CHB patients admitted to The First Hospital of Changsha from August 2019 to May 2021 were selected and divided into control group(40 cases,adefovir treatment) and observation group (40 cases,entecavir treatment) by coin grouping method,and the efficacy of the two groups were compared.Results There was no statistical significance in liver function before medication and incidence of adverse reactions after medication between two groups (P > 0.05).Compared with the control group,alanine aminotransferase (ALT),aspartate aminotransferase (AST) and total bilirubin (TBIL) in the observation group were lower after medication,and the total effective rate was higher,with statistical significance (P < 0.05).Conclusion Entecavir has a good curative effect on CHB patients and can improve their liver function.
作者
任孟群
谢雅
REN Meng-qun;XIE Ya(The First Hospital of Changsha,Hunan Changsha 410005)
出处
《深圳中西医结合杂志》
2021年第20期141-143,共3页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
