摘要
目的分析急性缺血性脑卒中患者溶栓后脑出血的危险因素。方法选取2018年4月至2019年4月本院收治的急性缺血性脑卒中患者85例作为研究对象。收集所有患者的一般资料(年龄、性别、糖尿病史、高脂血症史),检测患者舒张压(DBP)、收缩压(SBP),记录所有患者美国国立卫生研究院卒中量表(NIH stroke scale,NIHSS)评分,经多项Logistic回归分析急性缺血性脑卒中患者溶栓后脑出血的影响因素。结果 85例患者经溶栓治疗后,发生脑出血21例(观察组),未发生脑出血64例(对照组)。两组收缩压、舒张压、高脂血症、NIHSS评分比较差异有统计学意义(P<0.05)。非条件Logistic回归分析结果显示,收缩压及舒张压异常、有高脂血症、NIHSS>16分均为影响急性缺血性脑卒中患者溶栓后脑出血的危险因素(OR>1,P<0.05)。结论急性缺血性脑卒中患者溶栓后脑出血受收缩压及舒张压异常、有高脂血症、NIHSS>16分等因素影响,针对存在风险者,应积极采取干预。
Objective To analyze the risk factors of cerebral hemorrhage in patients with acute ischemic stroke after thrombolysis. Methods 85 patients with acute ischemic stroke admitted to our hospital from April 2018 to April 2019 were selected as the research subjects. Collected general information of all patients(age, gender, history of diabetes, history of hyperlipidemia), test diastolic blood pressure(DBP), systolic blood pressure(SBP), record all patients NIH stroke scale(NIHSS) scores, through multiple Logistic regression analysis to find out the influencing factors of cerebral hemorrhage after thrombolysis in patients with acute ischemic stroke. Results After thrombolytic therapy, 85 patients had cerebral hemorrhage in 21 cases(observation group), and 64 patients had no cerebral hemorrhage(control group). The difference in systolic blood pressure, diastolic blood pressure, hyperlipidemia, and NIHSS scores between the two groups was statistically significant(P<0.05). According to the results of unconditional Logistic regression analysis, abnormal systolic and diastolic blood pressure, hyperlipidemia, and NIHSS>16 scores are all risk factors affecting cerebral hemorrhage after thrombolysis in patients with acute ischemic stroke(OR>1, P<0.05). Conclusion Cerebral hemorrhage after thrombolysis in patients with acute ischemic stroke is affected by a variety of factors such as abnormal systolic and diastolic blood pressure, hyperlipidemia,NIHSS>16 scores, etc. For those at risk, intervention should be actively taken.
作者
李珊珊
LI Shanshan(Department of Neurology,Huludao Central Hospital,Huludao,Liaoning,125000,China)
出处
《当代医学》
2022年第3期46-48,共3页
Contemporary Medicine
关键词
急性缺血性脑卒中
溶栓
脑出血
危险因素
Acute ischemic stroke
Thrombolysis
Cerebral hemorrhage
Risk factors
