摘要
目的分析阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的中医体质类型特点,以及中医体质与病情严重程度、身体质量指数(BMI)、日间症状之间的关联性。方法采用横断面研究,对符合西医诊断标准的OSAHS患者106例进行基本信息表、中医体质量表、Epworth嗜睡量表(ESS)问卷调查,收集一般资料(性别、年龄、身体质量指数、合并病等)信息、记录多导睡眠呼吸监测报告的睡眠呼吸暂停低通气指数(AHI)结果,计算中医体质类型和ESS分值。对患者中医体质类型分布进行统计分析,对中医体质类型分布与OSAHS病情分度、BMI分级及与ESS分值差异进行相关性检验。结果 106例患者中超重及肥胖者88例,身体质量指数与病情分度呈正相关(r=0.220,P=0.024)。中医体质分布:平和质22例占20.8%,偏颇体质84例占79.3%,偏颇体质中单一偏颇体质18例,兼夹偏颇体质66例。每种体质在84例兼夹偏颇体质患者中排名前四位的依次是:痰湿质(42例),气虚质(42例),阴虚质(32例),湿热质(31例)。兼夹体质按两种偏颇体质共现计算频次,排名前四位的依次是:痰湿质+气虚质(28次),痰湿+湿热(20次),痰湿+阴虚(17次),气虚+湿热(17次)。仅痰湿质在不同病情分度中分布差异有统计学意义(P=0.004),与病情分度相关(r=0.282,P=0.003)。痰湿质、血瘀质BMI等级分布人数差异有统计学意义(P<0.05),BMI等级越高,痰湿质人数越多(r=0.314,P=0.04)。各体质类型ESS分值差异无统计学意义。结论阻塞性睡眠呼吸暂停低通气综合征患者多肥胖,体质以偏颇体质为主,位居前4位的是痰湿质、气虚质、阴虚质、湿热质,兼夹体质中痰湿质兼气虚质最多,重度OSAHS患者以痰湿质为主,痰湿质与超重程度和OSAHS病情严重程度相关。
Objective To describe the traditional Chinese medicine(TCM)constitution types among patients with obstructive sleep apnea hypopnea syndrome(OSAHS)and analyze the correlation between TCM constitution types and severity,boby mars index(BMI)and daytime symptoms of OSAHS.Methods This study was a cross-sectional study.A total of 106 patients meeting the diagnostic criteria of OSAHS were enrolled.Basic information(including gender,age,body mass index(BMI),comorbidities,etc.),the sleep apnea hypopnea index(AHI)of the polysomnography report results,TCM constitution type and ESS score were collected.Statistical analysis was performed on the distribution of TCM constitution types of patients,and the correlation analysis was performed on the distribution of TCM constitution types with OSAHS severity and with ESS scores.Results Among the 106 patients,88 were overweight and obese,and the BMI was positively correlated with the severity of the OSAHS(r=0.220,P=0.024).Distribution of TCM constitution types:the balanced constitution accounted for 20.8%with the remaining eight biased constitutions accounted for 79.3%.There were 18 cases of single biased constitution and 66 cases of compound biased constitution.The top four TCM constitutions in the 84 patients with biased constitutions are as follows:phlegm-dampness(42 cases),qi deficiency(42 cases),yin deficiency(32 cases),damp-heat(31 cases).The top four co-existing composite constitutions in the frequency ranking are:phlegm-dampness+qi deficiency(28 times),phlegm-dampness+damp-heat(20 times),phlegm-dampness+yin deficiency(17 times),qi deficiency+damp-heat(17 times).Only the distribution of phlegm-dampness pattern in different OSAHS severity was statistically different(P=0.004)and was related to disease severity(r=0.282,P=0.003).There was a statistically significant difference in the distribution of BMI grades of phlegm-dampness and blood stasis constitution(P<0.05).The higher the BMI,the greater the number of phlegm-dampness.There was no significant difference in the ESS scores o
作者
李梦真
史良恬
冯淬灵
杨嘉颐
杨倩怡
米芳
Li Mengzhen;Shi Liangtian;Feng Cuiling;Yang Jiayi;Yang Qianyi;Mi Fang(Department of Respiratory,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;Department of Traditional Chinese Medicine,Peking University People’s Hospital,Peking University,Beijing 100044,China)
出处
《北京中医药大学学报》
CAS
CSCD
北大核心
2021年第10期953-959,共7页
Journal of Beijing University of Traditional Chinese Medicine
基金
第四批全国中医(临床、基础)优秀人才研修项目(No.国中医药人教发2017-24号)
北京市中医管理局北京中医药科技发展资金项目(No.JJ2018-72)。
关键词
阻塞性睡眠呼吸暂停低通气综合征
中医体质
肥胖
痰湿质
气虚质
日间嗜睡
横断面研究
obstructive sleep apnea hypopnea syndrome(OSAHS)
traditional Chinese medicine constitution
obesity
phlegm-dampness
qi deficiency
daytime sleepiness
cross-sectional study
