摘要
目的探讨心脏磁共振组织特征追踪(cardiovascular magnetic resonance feature tracking,CMR-FT)技术对射血分数保留的肥厚型心肌病患者(hypertrophic cardiomyopathy preserved ejection fraction,HCMpEF)左心室功能的价值。材料与方法对70例HCMpEF患者及42例健康对照组行3.0 T心脏磁共振稳态自由进动序列扫描后,将图像导入CVI42后处理软件,测量左心基本功能参数及左室整体3D应变参数,包括:径向(radial)、周向(circumferential)及纵向(longitudinal)的峰值应变(peak strain,PS)、收缩期峰值应变率(peak systolic strain rate,PSSR)及舒张期峰值应变率(peak diastolic strain rate,PDSR),采用SPSS 26.0软件对两组参数进行统计学分析。结果HCMpEF组的各个方向的PS均低于健康对照组[径向:26.00(14.63)vs.32.39(10.55),周向:(-17.30±4.55)vs.(-19.67±3.73),纵向:(-8.14±3.25)vs.(-10.74±3.26),HCMpEF组vs.健康对照组,单位:%],差异具有统计学意义(P<0.005);HCMpEF组的各个方向的PSSR及PDSR均低于健康对照组[PSSR径向:1.55(0.94)vs.1.85(0.61),周向:-0.99(0.39)vs.-1.13(0.29),纵向:-0.49(0.38)vs.-0.67(0.28),单位:s-1,P<0.05;PDSR径向:-1.37(-0.86)vs.-2.17(1.35),周向:0.87(2.44)vs.1.16(0.53),纵向:0.46(0.24)vs.0.68(0.33),单位:s-1],差异具有统计学意义(P<0.001)。结论HCMpEF患者尽管射血分数保留,但是心脏收缩及舒张功能已经受损,CMR-FT定量分析技术可以为评价心脏功能提供新的依据。
Objective:To explore the value of CMR tissue feature tracking technology for left ventricular strain in patients with hypertrophic cardiomyopathy(HCMpEF)with ejection fraction preserved.Materials and Methods:Seventy HCMpEF patients and 42 normal subjects(control group)were scanned with 3.0 T CMR steady-state free precession sequence,and the images were imported into CVI42 post-processing software to measure the basic function parameters of the left heart and the overall 3D strain parameters of the left ventricle.Including:radial,circumferential and longitudinal peak strain(PS),peak systolic strain rate(PSSR),peak diastolic strain rate(PDSR).The SPSS 26.0 software was used for statistical analysis of the two groups of parameters.Results:The peak strain in all directions of the HCMpEF group was lower than that of the control group[radial:26.00(14.63)vs.32.39(10.55),circumferential:(-17.30±4.55)vs.(-19.67±3.73),longitudinal:(-8.14±3.25)vs.(-10.74±3.26),HCMpEF group vs.control group,unit:%],the difference was statistically significant(P<0.005);the PSSR and PDSR in each direction of HCMpEF group both are lower than the control group[PSSR radial:1.55(0.94)vs.1.85(0.61),circumferential:-0.99(0.39)vs.-1.13(0.29),longitudinal:-0.49(0.38)vs.-0.67(0.28),unit:s-1,P<0.05;PDSR radial:-1.37(-0.86)vs.-2.17(1.35),circumferential:0.87(2.44)vs.1.16(0.53),longitudinal:0.46(0.24)vs.0.68(0.33),unit:s-1],the difference was statistically significant(P<0.001).Conclusion:Although the ejection fraction is preserved in HCMpEF patients,the systolic and diastolic functions have been impaired.The CMR-FT quantitative analysis technology can provide a new basis for evaluating cardiac function.
作者
刘宇豪
李薇
欧阳丽娜
杨琴
王一帆
孙潇
朱力
LIU Yuhao;LI Wei;OUYANG Lina;YANG Qin;WANG Yifan;SUN Xiao;ZHU Li(Ningxia Medical University,Yinchuan 750000,China;Department of Radiology,Gansu Provincial People's Hospital,Lanzhou 730000,China;Department of Radiology,General Hospital of Ningxia Medical University,Yinchuan 750000,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2022年第1期31-36,共6页
Chinese Journal of Magnetic Resonance Imaging
基金
2020年宁夏自然科学基金(编号:2020AAC03420)
2020年度宁夏医科大学临床学院“一流学科建设”开放课题。
关键词
心脏磁共振
组织特征追踪
心功能
应变
肥厚型心肌病
射血分数
cardiovascular magnetic resonance
tissue feature tracking
heart function
strain
hypertrophic cardiomyopathy
ejection fraction
