摘要
目的研究调查子宫瘢痕妊娠子宫动脉栓塞术(uterine artery embolization,UAE)治疗侧支动脉的形成的危险因素。方法选取本院收治的子宫瘢痕妊娠患者127例为研究对象,所有患者均于UAE手术治疗时进行观察,评估患者术后侧支动脉的发生率,根据侧支动脉形成情况将患者分为侧支动脉组和非侧支动脉组,对两组患者的基础资料、临床各项检查指标等进行组间对比分析,并采用单因素分析和多因素Logistic回归分析探讨影响子宫瘢痕妊娠患者UAE术后侧支动脉形成的危险因素。结果经统计观察显示,在子宫瘢痕妊娠UAE手术期间共形成侧支动脉患者45例,发生率为35.43%。经单因素分析显示,侧支动脉组和非侧支动脉组患者在年龄、体重指数(body mass index,BMI)、吸烟史、饮酒史、孕周、文化程度、据上次剖宫产间隔、子宫肌瘤病史等基础、临床资料比较差异无统计学意义(P>0.05)。而两组患者在前置胎盘、盆腔炎症、妊娠期合并症、人工流产手术史、剖宫产次数等发生率差异有统计学意义(P<0.05)。通过设计Logistic多元回归分析方案并进行相应的变量赋值,经多因素分析显示前置胎盘史、盆腔炎症史、妊娠期合并症发生率高、人流手术史、剖宫产次数多等均为子宫瘢痕妊娠UAE治疗时侧支动脉形成的高危因素。结论我院子宫瘢痕妊娠UAE治疗期间侧支动脉形成有着较高的发生率,其中前置胎盘史、盆腔炎症史、妊娠期合并症发生率高、人流手术史、剖宫产次数多等均为侧支动脉形成的独立危险因素,应引起临床医师的高度关注。
Objective To investigate the risk factors of the formation of collateral artery in uterine artery embolization(UAE)for uterine scar pregnancy.Methods In total,127 patients with uterine scar pregnancy in our hospital were selected as the research subjects.All patients were observed during UAE operation.The incidence of collateral artery was evaluated and calculated.According to the formation of collateral artery,the patients were divided into collateral artery group and non-collateral artery group.A comparative analysis was performed on the basic data and clinical examination indicators of the two groups.The risk factors of collateral artery formation after UAE were analyzed by univariate analysis and multivariate Logistic regression analysis.Results According to the statistical observation,45 cases with collateral artery were found during UAE for uterine scar pregnancy,and the incidence was 35.43%.Univariate analysis showed that there was no significant difference in age,body mass index(BMI),smoking history,drinking history,gestational age,education level,time interval from the last cesarean section(C-section),history of hysteromyoma and other basic and clinical data between the two groups(P>0.05).There were significant differences in the incidence of placenta previa,pelvic inflammation,pregnancy complications,history of abortion,frequency of C-section between the two groups(P>0.05).Through the design of multiple Logistic regression analysis program and the corresponding variable assignment,the multivariate analysis showed that the history of placenta previa,the history of pelvic inflammation,the high incidence of complications during pregnancy,the history of abortion,and the number of C-section were the high-risk factors of collateral artery formation during UAE treatment for uterine scar pregnancy.Conclusion There is a high incidence of collateral artery formation during UAE treatment for uterine scar pregnancy in our hospital,among which the history of placenta previa and pelvic inflammation,high incidence of
作者
侯芳娟
韩宁
HOU Fang-juan;HAN Ning(Department of Obstetrics and Gynecology, No. 987 Hospital of Joint Logistics Support Force of Chinese PLA, Shaanxi Province, Baoji 721000, China)
出处
《河北医科大学学报》
CAS
2022年第1期75-79,共5页
Journal of Hebei Medical University
基金
陕西省医学科学研究重点课题计划(2016JM3987)。
关键词
子宫动脉栓塞术
妊娠并发症
瘢痕
uterine artery embolization
pregnancy complications
cicatrix
