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能谱CT碘图联合标准化碘浓度在甲状腺癌诊断中的应用价值

Application Value of Energy Spectrum CT Iodine Map Combined with Standard Iodine Concentration in the Diagnosis of Thyroid Cancer
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摘要 目的探讨能谱CT碘图联合标准化碘浓度在甲状腺癌诊断中的临床价值。方法选取2018年7月至2021年7月商丘市第一人民医院收治的80例甲状腺结节患者作为研究对象。所有患者入院时均在商丘市第一人民医院接受能谱CT检查并记录相关参数,择期进行病理检查。根据病理检查结果记录甲状腺癌检出情况,分析能谱CT碘图联合标准化碘浓度在甲状腺癌诊断中的应用价值。结果80例甲状腺结节经病理检查结果显示,25例(31.25%)确诊为甲状腺癌(恶性组),55例(68.75%)为良性结节(良性组),其中囊肿18例,炎症性结节28例,增生性结节型甲状腺肿9例。恶性组40 keV下CT值、90 keV下CT值、斜率K、碘浓度、有效原子序数、标准化碘浓度小于良性组(P<0.05)。恶性组水浓度与良性组比较,差异无统计学意义(P>0.05)。绘制受试者工作特征(ROC)曲线,结果显示,(40~90 keV)斜率K、碘浓度、有效原子序数、NIC单独及联合评估甲状腺癌患者的曲线下面积(AUC)均大于0.70,均有一定诊断价值,其中联合检测诊断价值最高。结论能谱CT碘图联合标准化碘浓度能够有效诊断甲状腺癌。 Objective To explore the clinical value of energy spectrum CT iodine map combined with standard iodine concentration in the diagnosis of thyroid cancer.Methods A total of 80 patients with thyroid nodules treated in Shangqiu First People’s Hospital from July 2018 to July 2021 were selected as the research subjects.All patients were examined by energy spectrum CT in the hospital when they were admitted to the hospital,and the related parameters were recorded,and pathological examination was performed at another time.According to the pathological examination results,the detection of thyroid cancer was recorded,and the application value of energy spectrum CT iodine diagram combined with standard iodine concentration in the diagnosis of thyroid cancer was analyzed.Results Pathological examination of 80 thyroid nodules showed that 25 cases(31.25%)were diagnosed as thyroid cancer(malignant group)and 55 cases(68.75%)were benign nodules(benign group),including 18 cysts,28 inflammatory nodules and 9 proliferative nodular goiter.The CT value at 40 keV and 90 keV,slope K,iodine concentration,effective atomic number and normalized iodine concentration in malignant group were lower than those in benign group(P<0.05).There was no statistical difference in water concentration between malignant group and benign group(P>0.05).The receiver operating characteristic(ROC)curve was drawn.The results showed that the area under the curve(AUC)of(40 to 90 keV)slope K,iodine concentration,effective atomic number,NIC alone and in combination for evaluating patients with thyroid cancer were all greater than 0.70.All of them had certain diagnostic value,and the diagnostic value of combined detection was the highest.Conclusion Energy spectrum CT iodine map combined with standard iodine concentration can effectively diagnose thyroid cancer.
作者 林光耀 黄文起 LIN Guangyao;HUANG Wenqi(Magnetic Resonance Imaging Room,Shangqiu First People’s Hospital,Shangqiu 476100,China)
出处 《河南医学研究》 CAS 2022年第1期165-168,共4页 Henan Medical Research
基金 河南省医学科技攻关计划联合共建项目(2018020940)。
关键词 甲状腺癌 能谱CT 碘图 标准化碘浓度 thyroid cancer energy spectrum CT iodine map standard iodine concentration
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