摘要
目的:分析^(18)F-脱氧葡萄糖(FDG)SPET/CT显像结合血清肿瘤标志物水平诊断肺癌的临床意义。方法:选取我院2019年1月—2021年4月期间收取的疑似为肺癌患者85例,术前分别经^(18)F-脱氧葡萄糖(FDG)SPET/CT显像检查,并采集患者外周静脉血,测定血清肿瘤标志物水平,计算其诊断价值。结果:联合方法检出灵敏度、特异度及准确性分别为93.94%、94.23%、94.12%,均高于^(18)F-FDG SPET/CT显像、血清肿瘤标志物,差异有统计学意义(P<0.05)。恶性组T/N值、NSE、CA125、CYFRA21-1及CEA表达均高于良性组(P<0.05)。结论:^(18)F-脱氧葡萄糖SPET/CT显像结合血清肿瘤标志物,可有效预测肺癌发生,可推广应用。
Objective To analyze the clinical significance of^(18)F-deoxyglucose(FDG)SPET/CT imaging combined with serum tumor marker levels in the diagnosis of lung cancer.Methods 85 patients with suspected lung cancer collected in our hospital from January 2019 to April 2021 were examined by^(18)F deoxyglucose(FDG)SPECT/CT before operation,and the peripheral venous blood was collected to measure the level of serum tumor markers and calculate its diagnostic value.Results The detection sensitivity,specificity and accuracy of the combined method were 93.94%,94.23%,and 94.12%,respectively,which were all higher than those of^(18)F-FDG SPET/CT imaging or serum tumor markers.The difference was statistically significant(P<0.05).The expressions of T/N,NSE,CA125,CYFRA21-1 and CEA in the malignant group were higher than those in the benign group(P<0.05).Conclusion^(18)F-deoxyglucose SPET/CT imaging combined with serum tumor markers can effectively predict the occurrence of lung cancer and can be popularized and applied.
作者
杨军荣
Yang Junrong(Department of Nuclear Medicine Diagnosis and Therapy,Jiangdu People's Hospital,Yangzhou,Jiangsu 225200,China)
出处
《影像研究与医学应用》
2021年第22期21-23,共3页
Journal of Imaging Research and Medical Applications
