摘要
报道了一种基于偏振敏感光学相干层析术的人体组织退偏特性在体测量方法。以人体手指指甲为样品,采用基于斯托克斯矢量的测量方法和基于宏观穆勒矩阵的测量方法,获得了指甲的不同退偏参数图像,并通过比较图像来衡量这两种方法的优劣。基于穆勒矩阵的方法获得的图像中,能明显区分出甲床结构,对比度高,但能显示出的结构较少。基于斯托克斯矢量的方法获得的图像中,不同偏振光在样品同一位置处获得的退偏均匀度值不同。选取45°偏振光计算其后向反射光的圆偏振度可以获得样品结构信息,包括指甲的甲板、甲床和甲基质下的真皮层。基于斯托克斯矢量法入射45°偏振光测量圆偏振度的方法计算量小,且提取出的结构信息最多,成像效果最好。
An in vivo method for measuring the depolarization characteristic of human tissues based on polarization-sensitive optical coherence tomography is proposed.Human finger nails are used as samples.Stokes vector and the macroscopic Mueller matrix measurement methods are adopted to obtain images of different depolarization parameters of nails.The advantages and disadvantages of these two methods are measured by comparing the images.In the images generated by the Mueller matrix-based method,the nail bed structure can be clearly distinguished.It has high contrast,but with showing less structure clearly.In the Stokes vector-based method,the depolarization uniformity values obtained by different irradiation polarized light at the same position are different.The 45°polarized light is selected to calculate the circular polarization of its backward reflected light which derives the structural information of the sample,including the nail plate,the nail bed and the dermis under the nail matrix.The circular polarization measurement method based on Stokes vector incident 45°polarized light has a small amount of calculation,and extracts the most structural information,and the imaging effect is the best.
作者
吴东瑾
高万荣
常颖
WU Dongjin;GAO Wanrong;CHANG Ying(School of Electronic Engineering and Optoelectronic Technique,Nanjing University of Science and Technology,Nanjing 210094,China)
出处
《光子学报》
EI
CAS
CSCD
北大核心
2021年第12期168-175,共8页
Acta Photonica Sinica
基金
中央高校基本科研业务费专项资金(No.30920010003)
国家自然科学基金(Nos.61275198,60978069)。
关键词
生物医学成像
偏振敏感光学相干层析术
斯托克斯矢量
穆勒矩阵
退偏
Biomedical imaging
Polarization-sensitive optical coherence tomography
Stokes vector
Mueller matrix
Depolarization
