摘要
目的探讨急性上消化道出血(AUGIB)患者并发心肌损伤的危险因素。方法抽取2018年1月至2020年1月晋城市人民医院收治的65例AUGIB患者为研究对象,所有患者均于入院72 h内接受血清心肌肌钙蛋白I(cTnI)检测,根据cTnI结果将患者分为心肌损伤组与无心肌损伤组。收集患者的年龄、性别、既往史等一般资料,检测患者血生化、心肌损伤标志物水平等实验室指标,分析AUGIB患者心肌损伤的发生情况,并对其危险因素进行Logistic回归分析。结果65例AUGIB患者经cTnI检测显示23例(35.38%)合并心肌损伤,将其纳入心肌损伤组;另42例患者纳入非心肌损伤组。两组年龄、舒张压、血红蛋白、红细胞压积、白蛋白、尿素氮、肌酐及高血压病史比较差异均有统计学意义(P均<0.05)。多因素Logistic回归分析结果显示,高龄、舒张压低、低血红蛋白、高尿素氮及高血压病史是AUGIB患者发生心肌损伤的独立危险因素(P<0.05)。结论AUGIB患者存在较高的心肌损伤发生风险,高龄、高血压病史、舒张压低、低血红蛋白、高尿素氮均是发生心肌损伤的独立危险因素。
Objective To investigate the risk factors of myocardial injury in patients with acute upper gastrointestinal bleeding(AUGIB).Methods Sixty-five patients with AUGIB treated in Jincheng People’s Hospital from January 2018 to January 2020 were selected as the research objects.All patients received the detection of serum cardiac troponin I(cTnI)within 72 hours after admission.According to the results of cTnI,the patients were divided into myocardial injury group and no myocardial injury group.The age,gender,and past medical history of the patients were collected.The levels of blood biochemistry and myocardial injury markers were detected.The occurrence of myocardial injury in AUGIB patients was analyzed,and its risk factors were analyzed by Logistic regression.Results The detection of cTnI in 65 patients with AUGIB showed that 23 cases(35.38%)were complicated by myocardial injury,and they were included into myocardial injury group;the other 42 cases were included into non-myocardial injury group.There were significant differences in age,diastolic blood pressure,hemoglobin,hematocrit,albumin,urea nitrogen,creatinine and history of hypertension between the two groups(all P<0.05).Results of multivariate Logistic regression analysis showed that age,diastolic blood pressure,hemoglobin,urea nitrogen,and history of hypertension were independent risk factors for myocardial injury in AUGIB patients(P<0.05).Conclusions Patients with AUGIB have a high risk of myocardial injury.Advanced age,hypertension,diastolic blood pressure,hemoglobin and urea nitrogen are independent risk factors of myocardial injury.
作者
张妮娜
张曙光
Nina Zhang;Shuguang Zhang(Department of Gastroenterology,Jincheng People’s Hospital,Jincheng 048026,China;Department of Stomatology,Jincheng People’s Hospital,Jincheng 048026,China)
出处
《中国实用医刊》
2021年第21期55-59,共5页
Chinese Journal of Practical Medicine
关键词
消化道出血
心肌损伤
影响因素
Gastrointestinal bleeding
Myocardial injury
Influencing factors
