摘要
目的:研究对慢性肾衰竭尿毒症期患者应用高通量血液透析与常规血液透析治疗的疗效差异性。方法:抽选于2018年12月~2020年2月本院收治的慢性肾衰竭尿毒症期患者100例,根据双盲法均分为两组。对照组(n=50)接受常规血液透析治疗,研究组(n=50)接受高通量血液透析治疗。评价及对比两组的疗效、肾功能指标、并发症发生情况。结果:由治疗疗效数据方面上可见,研究组的总有效率高于对照组(P<0.05)。由肾功能指标数据方面上可见,研究组的SCr、β2-MG、BUN水平均低于对照组(P<0.05)。由钙磷代谢水平指标方面上可见,治疗前两组数据经统计学分析后差异无意义(P>0.05),治疗后对照组数据差于研究组(P<0.05)。由炎症因子水平数据表明,治疗前两组数据经统计学分析后差异无意义(P>0.05),治疗后对照组数据高于研究组(P<0.05)。由并发症发生率方面上可见,研究组并发症发生率为4.00%(2/50);对照组并发症发生率为16.00%(8/50);研究组的并发症发生率低于对照组(P<0.05)。治疗后患者的瘙痒程度表明,对照组明显高于研究组(P<0.05)。结论:对慢性肾衰竭尿毒症期患者应用高通量血液透析的疗效优于常规血液透析,治疗优势明显,可有效改善肾功能,且并发症少,具有良好的临床应用价值。
Objective:To study the difference in curative effect between high flux hemodialysis and conventional hemodialysis in patients with chronic renal failure and uremia.Methods:A total of 100 patients with chronic renal failure and uremia who were admitted to our hospital from December 2018 to February 2020 were selected and divided into two groups according to the double-blind method.The control group(n=50)received conventional hemodialysis treatment,and the study group(n=50)received high-throughput hemodialysis treatment.Evaluate and compare the curative effect,renal function indexes,and complications of the two groups.Results:It can be seen from the data of treatment efficacy that the total effective rate of the study group is higher than that of the control group(P<0.05).It can be seen from the data of renal function indexes that the levels of SCr,β2-MG,and BUN in the study group were lower than those in the control group(P<0.05).It can be seen from the indicators of calcium and phosphorus metabolism levels that there is no significant difference between the two groups of data before treatment after statistical analysis(P>0.05),and the data of the control group after treatment is worse than the study group(P<0.05).According to the inflammatory factor level data,there is no significant difference between the two groups of data before treatment after statistical analysis(P>0.05),and the data of the control group after treatment is higher than that of the study group(P<0.05).It can be seen from the complication rate that the complication rate of the study group was 4.00%(2/50);the complication rate of the control group was 16.00%(8/50);the complication rate of the study group was lower than that of the control group(P<0.05).The degree of itching of patients after treatment showed that the control group was significantly higher than that of the study group(P<0.05).Conclusion:The effect of high flux hemodialysis on patients with chronic renal failure in the uremic phase is better than that of conventional hemodialysis
作者
郭馨
张东成
GUO Xin;ZHANG Dong-cheng(Department of Nephrology,Liaoning Provincial People’s Hospital,Liaoning Shenyang 110016)
出处
《中国医疗器械信息》
2021年第24期34-36,共3页
China Medical Device Information
关键词
慢性肾衰竭尿毒症
高通量血液透析
常规血液透析
chronic renal failure uremia
high flux hemodialysis
conventional hemodialysis
