摘要
目的分析2型糖尿病合并胃溃疡患者采用泮托拉唑与维生素C治疗的价值。方法筛选2020年1月—2021年4月该院收治的80例2型糖尿病合并胃溃疡患者作为研究对象,按"随机法"分观察组和对照组,每组40例。对照组实施泮托拉唑治疗,观察组实施泮托拉唑+维生素C治疗,对比两组临床疗效、不良反应率、临床指标、生活质量。结果观察组总有效率(97.50%)高于对照组(82.50%),观察组不良反应率(7.50%)低于对照组(25.00%),差异有统计学意义(χ^(2)=5.000、4.501,P<0.05);治疗后观察组空腹血糖(6.74±0.42)mmol/L、餐后2 h血糖(9.21±0.56)mmol/L、糖化血红蛋白(5.02±2.21)%、胆固醇(4.41±0.82)mmol/L、三酰甘油(1.91±0.72)mmol/L、TyG指数(1.02±0.24)%低于对照组,差异有统计学意义(t=6.823、9.405、3.302、4.721、3.799、5.690,P<0.05);观察组社会评分(94.24±2.42)分、精神评分(91.43±4.11)分、躯体评分(94.24±3.42)分、情绪评分(94.34±4.91)分、活力评分(93.44±3.44)分、总的健康评分(92.34±2.46)分等维度生活质量评分高于对照组,差异有统计学意义(t=7.759、10.457、18.411、11.406、10.431、11.033,P<0.05)。结论选择泮托拉唑与维生素C对2型糖尿病合并胃溃疡进行治疗可改善其血糖、血脂水平,亦可提高治疗安全性、有效性。
Objective To analyze the value of pantoprazole and vitamin C in patients with type 2 diabetes and gastric ulcer.Methods The 80 patients with type 2 diabetes and gastric ulcer who were admitted to the hospital from January 2020 to April 2021 were selected as the research objects. According to the "random method", they were divided into observation group and control group, with 40 cases in each group. The control group was treated with pantoprazole, and the observation group was treated with pantoprazole + vitamin C. The clinical efficacy, adverse reaction rate, clinical indicators, quality of life were compared between the two groups. Results The total effective rate of the observation group(97.50%) was higher than that of the control group(82.50%), and the adverse reaction rate of the observation group(7.50%) was lower than that of the control group(25.00%), the difference was statistically significant(χ2=5.000, 4.501, P<0.05);after treatment, the fasting blood glucose of observation group was(6.74±0.42) mmol/L, postprandial 2 h blood glucose(9.21±0.56) mmol/L,HbA1 c(5.02±2.21) %, cholesterol(4.41±0.82) mmol/L, triacylglycerol(1.91 ±0.72) mmol/L and TyG index(1.02±0.24) %were lower than those in control group, the difference was statistically significant(t =6.823, 9.405, 3.302, 4.721, 3.799,5.690, P<0.05);the scores of social score(94.24±2.42) points and mental score(91.43±4.11) points, body score(94.24±3.42)points, mood score(94.34±4.91)points, vitality score(93.44 ±3.42) points, total health score(92.34 ±2.46) points in the observation group were higher than those in the control group, and the differences were statistically significant(t =7.759,10.457, 18.411, 11.406, 10.431, 11.033, P<0.05). Conclusion Choosing pantoprazole and vitamin C to treat type 2 diabetes with gastric ulcer can improve the blood glucose and blood lipid levels, and also improve the safety and effectiveness of the treatment. It is worthy of reference.
作者
刘晓成
LIU Xiaocheng(Department of Gastroenterology,Putian Hanjiang Hospital,Putian,Fujian Province,351111 China)
出处
《糖尿病新世界》
2021年第21期102-105,共4页
Diabetes New World Magazine
关键词
泮托拉唑
维生素C
2型糖尿病
胃溃疡
疗效
安全性
TyG指数
Pantoprazole
Vitamin C
Type 2 diabetes mellitus
Gastric ulcer
Curative effect
Safety
TyG index
