摘要
目的利用中医传承辅助系统平台,分析期刊文献中采用中医药治疗肛窦炎的用药组方规律。方法筛选自建库至2021年2月发表在中国知网、中文科技期刊全文数据库、万方数据库中关于中医药治疗肛窦炎的文献,数据录入中医传承辅助系统平台,采用软件的数据分析模块,分析中医治疗肛窦炎的用药规律,分析用药的四气、五味、归经、药物使用频次、组方规律和潜在的新方组合。结果共纳入49首处方,涉及中药118味。药物以寒性药(202次)为主;以苦味药(263次),甘味药(150次),辛味药(109次)为主,主要归肝经(145次)、脾经(132次)、胃经(107次)、肺经(99次),用药频次最多的六味药是黄柏(26次)、甘草(21次)、黄连(18次)、当归(14次)、地榆(13次)和苦参(13次),前6位药对组合为当归-生地黄、甘草-枳壳、当归-甘草、黄柏-地榆、甘草-黄连、蒲公英-野菊花;共挖掘出用于新方的核心药物组合6个。结论目前已知的中医治疗肛窦炎的方剂以清热祛湿、凉血解毒为主,兼有疏肝、活血止痛等,其核心药物组合及新处方对肛窦炎的理论研究、新药开发及临床辨证治疗具有一定的参考价值。
Objective To analyze the prescription rules of treating anal sinusitis with traditional Chinese medicine in periodical literature by using traditional Chinese medicine inheritance support system platform.Methods The literatures on traditional Chinese medicine treatment of anal sinusitis published in China National Knowledge Infrastructure,Chinese sci-tech Periodical Full-text Database and Wanfang Database from inception to February 2021 were screened,and the data were input into the traditional Chinese medicine inheritance support system platform.The data analysis module of the software was used to analyze the medication rule of traditional Chinese medicine in the treatment of anal sinusitis,including four nature of drugs,five flavours,channel tropism,drug use frequency,prescription rule and potential new prescription combination.Results A total of 49 prescriptions involving 118 traditional Chinese medicine were included.Drugs were mainly cold drugs(202 times),bitter drugs(263 times),sweet drugs(150 times),spicy drugs(109 times),mainly through the liver meridian(145 times),spleen meridian(132 times),stomach meridian(107 times),lung meridian(99 times).The six most frequently used herbs were amur cork-tree(26 times),liquorice root(21 times),golden thread(18 times),chinese angelica(14 times),garden burnet root(13 times)and lightyellow sophora root(13 times).The first six drug pairs were chinese angelica-unprocessed rehmannia root,liquorice root-orange fruit,chinese angelica-liquorice root,amur cork-tree-garden burnet root,liquorice root-golden thread,dandelion-wild chrysanthemum flower.A total of six core drug combinations for the new formula were excavated.Conclusion At present,the known traditional Chinese medicine prescriptions for the treatment of anal sinusitis are mainly to clear heat and remove diuresis,cool blood and detoxify,and also to soothe liver,promote blood circulation and relieve pain,etc.The core drug combinations and new prescriptions have certain reference value for the theoretical research,new dr
作者
于大远
刘薇
李雪
刘仍海
YU Dayuan;LIU Wei;LI Xue;LIU Renghai(Department of Proctology,Dongfang Hospital of Beijing University of Chinese Medicine,Beijing100078,China)
出处
《中国医药导报》
CAS
2021年第34期126-130,共5页
China Medical Herald
基金
北京中医药科技发展资金项目(JJ2016-75)。
关键词
肛窦炎
中医传承辅助系统平台
用药组方规律
数据挖掘
Anal sinusitis
Traditional Chinese medicine inheritance support system platform
Prescription law
Data mining
