摘要
目的采用数据挖掘方法探讨针灸治疗干眼的临床应用规律。方法检索中国期刊全文数据库(CNKI)、中文科技期刊数据库(维普网)、中国学术期刊数据库(万方数据)、中国生物医学文献数据库(CBM)、Pub Med、Web of Science、Cochrane Library 2010年1月1日-2020年12月1日收录的针灸治疗干眼的临床文献,建立文献信息数据库,对腧穴进行描述性分析、聚类分析及关联规则分析,归纳腧穴配伍规律。结果共纳入264篇临床文献,获得373条组方,涉及腧穴120个、耳穴18个、眼针穴8个、头针刺激区2个。足太阳膀胱经的腧穴应用频次最高,选穴部位主要在面部,特定穴以交会穴和五输穴为主;聚类分析得到三阴交-足三里-太冲-太溪-风池、攒竹-四白-太阳、睛明-合谷-承泣-丝竹空3类腧穴配伍;关联规则分析得出攒竹→睛明、攒竹→太阳、攒竹→三阴交等12个强关联腧穴组合。针刺、针刺+中药、针刺+西药滴眼液为主要治疗方法,3种方法对泪膜破裂时间、泪液分泌量、角膜荧光素染色评分均有一定改善作用。不良事件以针刺后皮下淤血最多。结论针灸治疗干眼常用腧穴为攒竹、睛明、太阳等,常用耳穴为肝、眼、内分泌等。治疗方法以针刺或针刺配合药物为主。
Objective To explore the clinical application rules of acupuncture and moxibustion in treating dry eye(DE).Methods Literature on acupuncture and moxibustion in treating DE published from January 1 of 2010 to December 1 of 2020 was retrieved from databases of CNKI,VIP,Wanfang Data,CBM,PubMed,Web of Science,and Cochrane Library.The literature information database was established,descriptive analysis,clustering analysis and association rule analysis of acupoints were carried out,and the compatibility rules of acupoints were summarized.Results A total of 264 clinical articles were included for statistical analysis,and 373 prescriptions,120 acupoints,18 auricular acupoints,8 ophthalmic acupoints and 2 scalp acupoint lines were obtained.Acupoints on Bladder Meridian of Foot-Taiyang were used most frequently,and the selected acupoints were mainly concentrated on the face.The selected specific acupoints were mainly confluent acupoints and Five-shu acupoints.A total of three kinds of acupoints compatibility:Sanyinjiao(SP6)-Zusanli(ST36)-Taichong(LR3)-Taixi(KI3)-Fengchi(GB20);Cuanzhu(BL2)-Sibai(ST2)-Taiyang(EX-HN5);Jingming(BL1)-Hegu(LI4)-Chengqi(ST1)-Sizhukong(TE23).Association rules analysis obtained 12 strong correlation acupoints including Cuanzhu(BL2)→Jingming(BL1),Cuanzhu(BL2)→Taiyang(EX-HN5),Cuanzhu(BL1)→Sanyinjiao(SP6)and others.Acupuncture or acupuncture combined with Chinese materia medica,acupuncture combined with Western medicine eyedrops were the main therapeutic methods in clinical research.The three methods had a certain improvement effect on tear film rupture time,tear secretion and corneal fluorescein staining score.The most adverse events were subcutaneous congestion after acupuncture.Conclusion Cuanzhu(BL2),Jingming(BL1),Taiyang(EX-HN5)are commonly used acupoints in acupuncture and moxibustion treatment for DE.Liver(CO12),Eye(LO5),and Endocrine(CO18)are commonly used auricular acupoints.The clinical treatment of DE is mainly acupuncture or acupuncture combined with medicine.
作者
郭潇聪
杨延婷
董小庆
韩榕
刘婕
洪珏
张丹
马晓芃
GUO Xiaocong;YANG Yanting;DONG Xiaoqing;HAN Rong;LIU Jie;HONG Jue;ZHANG Dan;MA Xiaopeng(Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Shanghai Research Institute of Acupuncture and Meridian,Shanghai 200030,China)
出处
《中国中医药信息杂志》
CAS
CSCD
2022年第1期26-32,共7页
Chinese Journal of Information on Traditional Chinese Medicine
基金
国家自然科学基金青年基金(81904302)
上海市卫生健康委员会项目(201840174、201940130)
上海市青年科技英才扬帆计划项目(19YF1445000)
上海中医药大学“研究生创新培养专项”(Y2020019)。
关键词
针灸疗法
干眼
临床应用规律
数据挖掘
acupuncture and moxibustion therapy
dry eye
clinical application rules
data mining
