摘要
目的探究枸橼酸钠输注对单采血小板献血者胃肠道存在的影响,提出防控措施并评价其应用效果。方法采集2020年6月至2021年6月单采血小板献血者200例作为本次研究对象。根据不同护理模式将其分成对照组(100例,常规干预)与观察组(100例,综合干预)。统计研究对象胃肠道反应发生情况,观察比较两组献血者健康状况。结果200例献血者8例出现胃肠反应,总发生率4.00%;观察组仅见1例恶心,胃肠道反应发生率1.00%,较对照组7.00%(恶心2例、呕吐2例、腹泻2例、腹痛1例)低(P>0.05);观察组采血后血清PTH[(3.28±0.47)pmol/L]、Mg^(+)[(0.95±0.17)mmol/L]、K^(+)[(4.44±0.56)mmol/L]、Ca^(2+)[(1.13±0.18)mmol/L]水平与采血前[(3.23±0.45)pmol/L、(0.96±0.14)mmol/L、(4.42±0.26)mmol/L、(1.12±0.13)mmol/L]比较,差异无统计学意义(P<0.5),除K^(+)与采血后对照组[(4.45±0.54)mmol/L]差异不大,其他指标与对照组[(3.02±0.58)pmol/L、(0.89±0.11)mmol/L、(0.94±0.11)mmol/L]差异均有统计学意义(P<0.05);观察组枸橼酸中毒发生率4.00%,低于对照组的16.00%(P<0.05),严重程度更轻;观察组舒适度(心理、生理、精神、社会文化和环境以及总分)评分[(23.32±2.02)分、(22.68±2.41)、(22.69±2.52)分、(23.02±2.47)分、(89.98±5.69)分]高于对照组[(19.02±2.32)分、(18.17±2.33)分、(18.65±2.17)分、(19.68±2.36)分、(76.69±4.32)分](P<0.05)。结论枸橼酸钠输注可在一定程度上导致单采血小板献血者出现胃肠道反应,发生枸橼酸钠中毒问题,给予献血者钙剂处理与有效干预可降低枸橼酸钠输注影响,降低枸橼酸钠中毒发生率,提高献血者舒适度。
Objective To explore the effect of sodium citrate infusion on gastrointestinal tract of platelet donors,put forward prevention and control measures and evaluate its application effect.Methods A total of 200 platelet donors were collected from June 2020 to June 2021.According to different nursing modes,they were divided into control group(100 cases,routine intervention)and observation group(100 cases,comprehensive intervention).The incidence of gastrointestinal reactions was counted,and the health status of blood donors in the two groups was observed and compared.Results Eight of 200 blood donors had gastrointestinal reactions,with a total incidence of 4.00%.There was only one case of nausea in the observation group,and the incidence of gastrointestinal reaction was 1.00%,which was lower than 7.00%in the control group(2 cases of nausea,2 cases of vomiting,2 cases of diarrhea and 1 case of abdominal pain)(P>0.05).The serum PTH[(3.28±0.47)pmol/L],Mg^(+)[(0.95±0.17)mmol/L],K^(+)[(4.44±0.56)mmol/L],Ca^(2+)[(1.13±0.18)mmol/L]levels in the observation group after blood collection had no significant difference from those before blood collection[(3.23±0.45)pmol/L,(0.96±0.14)mmol/L,(4.42±0.26)mmol/L,(1.12±0.13)mmol/L](P<0.5).Except that there was no significant difference between K^(+) and control group[(4.45±0.54)mmol/L],other indexes were significantly different from control group[(3.02±0.58)pmol/L,(0.89±0.11)mmol/L,(0.94±0.11)mmol/L](P<0.05).The incidence of citric acid poisoning in the observation group was 4.00%,which was lower than 16.00%in the control group(P<0.05).The scores of comfort(psychology,physiology,spirit,social culture,environment and total scores)[(23.32±2.02),(22.68±2.41),(22.69±2.52),(23.02±2.47),(89.98±5.69)]were higher than those in the control group[(19.02±2.32),(18.17±2.33),(18.65±2.17),(19.68±2.36),(76.69±4.32)](P<0.05).Conclusion Sodium citrate infusion can lead to gastrointestinal reaction and sodium citrate poisoning in platelet donors.Calcium treatment and effective inter
作者
魏恩钲
张捷
郑小玲
WEI Enzheng;ZHANG Jie;ZHENG Xiaoling(Department of Blood Donation Service,Sanming Central Blood Station,Sanming 365000,China)
出处
《中国医药指南》
2021年第35期66-68,共3页
Guide of China Medicine
关键词
献血
枸橼酸钠
单采血小板
胃肠道
Blood donation
Sodium citrate
Apheresis platelets
Gastrointestinal tract
