摘要
目的:观察静脉溶栓联合介入治疗在急性脑梗死患者中的应用效果。方法:选取80例急性脑梗死患者为研究对象,按照随机数字表法分为观察组与对照组各40例。对照组行静脉溶栓治疗,观察组在对照组基础上行介入治疗,比较两组疗效、美国国立卫生研究院卒中量表(NIHSS)评分、复发率和出血事件发生率。结果:观察组治疗总有效率为92.50%,明显高于对照组的75.00%,差异有统计学意义(P<0.05);治疗后2 h、24 h、7 d,观察组NIHSS评分均低于对照组,差异有统计学意义(P<0.05);随访6个月,观察组复发率明显低于对照组,差异有统计学意义(P<0.05);两组出血事件发生率比较,差异无统计学意义(P>0.05)。结论:静脉溶栓联合介入治疗急性脑梗死患者可提高治疗总有效率,降低NIHSS评分和复发率,效果优于单纯静脉溶栓治疗。
Objective:To observe application effects of intravenous thrombolysis combined with interventional therapy in patients with acute cerebral infarction.Methods:80 patients with acute cerebral infarction were selected as the research objects,and were divided into observation group and control group according to the random number table method,40 cases in each group.The control group received intravenous thrombolysis,while the observation group was given interventional therapy based on that of the control group.The efficacy,the national institutes of health stroke scale(NIHSS)score,the recurrence rate and the bleeding event rate were compared between the two groups.Results:The total effective rate of treatment in the observation group was 92.50%,which was significantly higher than 75.00%in the control group,and the difference was statistically significant(P<0.05).2 h,24 h,and 7 d after the treatment,the NIHSS scores of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).After 6 months of follow-up,the recurrence rate of the observation group was significantly lower than that of the control group,and the difference was statistically significant(P<0.05);however,the difference in the incidence of bleeding events between the two groups was not statistically significant(P>0.05).Conclusions:Intravenous thrombolysis combined with interventional therapy for the patients with acute cerebral infarction can increase the total effective rate of treatment,and reduce the NIHSS score and the recurrence rate.Moreover,it is superior to simple intravenous thrombolysis.
作者
张洪淞
刘擎
ZHANG Hongsong;LIU Qing(1st Department of Neurology of the Central Hospital of Jiamusi City,Jiamusi 154002 Heilongjiang,China;2nd Department of Cardiology of the First Affiliated Hospital of Jiamusi University,Jiamusi 154002 Heilongjiang,China)
出处
《中国民康医学》
2021年第22期24-25,28,共3页
Medical Journal of Chinese People’s Health
关键词
急性脑梗死
静脉溶栓
介入治疗
NIHSS评分
复发率
出血事件
Acute cerebral infarction
Intravenous thrombolysis
Interventional therapy
NIHSS score
Recurrence rate
Bleeding event
