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石家庄市大肠息肉发病的危险因素及临床特征 被引量:6

The risk factors and clinic characteristics of colorectal polypsin in Shijiazhuang city
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摘要 目的探讨大肠息肉发病的好发因素及临床特征。方法选取2015年12月至2020年12月石家庄市人民医院门诊及住院行电子肠镜检查的患者,其中大肠息肉组560例,正常对照组240例,收集2组患者的年龄、性别、血脂、炎症指标、相关疾病及大便性状的改变,对大肠息肉发病的性别、年龄、好发因素、单发或多发、部位、大小、病理及镜下治疗进行分析总结。结果大肠息肉人群中男性多于女性,>40岁多发;高体重指数(BMI)、经常吸烟、饮酒、患有高脂血症(TG)、高胆固醇血症(TC)、高血压、较高炎症指标中性粒细胞/淋巴细胞比值(NLR)、血小板与淋巴细胞比值(PLR)易发生大肠息肉,临床上常以腹痛和腹泻为主,以多发息肉为主,病理以腺瘤为主,镜下治疗以高频电切术为主。结论高BMI、吸烟、饮酒、高脂血症、高胆固醇血症、高血压及较高炎症指标为大肠息肉发生的危险因素,临床上多以腹痛和腹泻为主,好发部位以左半结肠、多发、直径≤0.5 cm、山田Ⅰ型为主,病理以管状腺瘤为主,镜下治疗以高频电切术为主,并发症少,随访观察18.21%患者易复发。 Objective To investigate the risk factors and clinic characteristics of colorectal polypsin in Shijiazhuang city.Methods A total of 560 patients with colorectal polyps who were diagnosed by electronic colonoscopy in our hospital from December 2015 to December 2020 were enrolled as observation group,and 240 healthy subjects were enrolled as control group.The subjects’age and gender,blood lipid,inflammatory indexes,and the related diseases and changes of stool characteristics were observed and compared between the two groups.Moreover the patient’s gnder and age,risk factors,single or multiple occurrence,polyps site,pathology and endoscopic treatment of colorectal polyps were analyzed.Results The male patients with colorectal polyps were more than female patients,and the patients over 40 years of age,with high body mass index(BMI),smoking,drinking,hyperlipidemia(TG),cholesterol(TC),high blood pressure,higher ratio of neutrophils/lymphocyte(NLR),platelet and lymphocyte ratio(PLR)were more likely to suffer from colorectal polyps.The abdominal pain and diarrhea were the main symptoms,and multiple polyps predominated clinically,pathological type was mainly adenoma,and its treatment method was mainly high frequency electrotomy under endoscope.Conclusion The higher BMI,smoking,drinking,hyperlipidemia,hypercholesterolemia,hypertension,and high inflammation indexes are the risk factors of colon polyps,and the main symptoms are abdominal pain and diarrhea,which locates commonly in left colon,with multiple polyps,diameter≤0.5 cm,and pathological type is mainly tubular adenoma.Moreover endoscopic high frequency electroresection is common treatment method due to fewer complications,and follow up results show that 18.21%of patients are easy to relapse.
作者 牛学敏 赵树巧 贾彦红 薛辉 张晓博 张新元 NIU Xuemin;ZHAO Shuqiao;JIA Yanhong(Department of Gastroenterology,People’s Hospital of Shijiazhuang City,Hebei,Shijiazhuang 050011,China)
出处 《河北医药》 CAS 2021年第24期3825-3828,共4页 Hebei Medical Journal
基金 石家庄市科学技术研究与发展计划项目(编号:171462163)。
关键词 大肠息肉 危险因素 BMI 血脂 NLR PLR 临床特征 colorectal polyps risk factors body mass index blood lipid neutrophils/lymphocyte ratio platelet/lymphocyte ratio clinical features
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