摘要
以自制的钯碳为催化剂,2,6-二氯-3-三氟甲基吡啶为原料,经选择性加氢反应,制备得到2-氯-3-三氟甲基吡啶。考察了载体类型、Pd负载量、反应温度、缚酸剂对反应的影响。在最佳的反应条件下,2,6-二氯-3-三氟甲基吡啶的转化率可达94.8%,2-氯-3-三氟甲基吡啶的选择性可达96.5%。
Applied self-prepared Pd/C as catalyst,2-chloro-3-trifluoromethylpyridine was prepared by selective hydrogenation of 2,6-dichloro-3-trifluoromethylpyridine.The effects of the character of support,the amount of palladium,the temperature and acid-binding agent on the reaction were investigated.The conversion of 2,6-dichloro-3-trifluoromethylpyridine was 94.8%and the selectivity of 2-chloro-3-trifluoromethylpyridine was 96.5%under the optimum reaction conditions.
作者
陈洪龙
岳瑞宽
王文魁
罗超然
丁永山
CHEN Honglong;XUE Ruikuan;WANG Wenkui;LUO Chaoran;DING Yongshan(Nanjing Red Sun Biochemical Co.,Ltd.,Nanjing 210047,China)
出处
《化工技术与开发》
CAS
2021年第12期20-21,25,共3页
Technology & Development of Chemical Industry
