摘要
脓毒性休克指脓毒症合并严重的循环障碍和细胞代谢紊乱,其发生率、病死率高,病情凶险,是儿科重症监护病房患儿死亡的主要原因之一。因此,脓毒性休克的早期诊断和有效治疗至关重要。其中,液体复苏占据重要地位,但是,近几年的研究对后续的液体平衡管理问题争议颇多。本文将从液体平衡治疗方面入手,着重探讨大剂量液体复苏对脓毒性休克患儿预后的影响,为儿童脓毒症液体治疗的完善作一参考。
Septic shock refers to sepsis combined with severe circulatory disorders and cell metabolism disorders,with high incidence,high fatality rate,and dangerous condition.It is one of the leading cause of death in children in pediatric intensive care units.Therefore,early diagnosis and effective treatment of septic shock are very important.Among them,fluid resuscitation is an important part of treatment.However,the research in recent years has a lot of controversy about subsequent fluid balance management issues.This review summarized fluid balance therapy,focusing on the large dose of fluid resuscitation on the prognosis of children with septic shock,aiming to provide a reference for the future improvement of fluid therapy for children with sepsis.
作者
张家赫
王丽杰
Zhang Jiahe;Wang Lijie(Pediatric Intensive Care Unit,Shengjing Hospital of China Medical University,Shenyang 110004,China)
出处
《中国小儿急救医学》
CAS
2021年第11期993-997,共5页
Chinese Pediatric Emergency Medicine
基金
辽宁省科技重大专项计划(2020JH1/10300001)。
关键词
脓毒性休克
感染
液体平衡
大剂量
液体复苏
儿童
Septic shock
Infection
Fluid balance
High-dose
Fluid resuscitation
Children