摘要
目的分析脉搏指示连续心排血量监测(PICCO)指导液体负平衡治疗感染性休克患者的早期复苏及预后影响。方法选取2020年7月—12月信丰县人民医院感染性休克患者74例,按治疗方法不同分为研究组(n=37)与对照组(n=37),对照组采用PICCO指导液体复苏治疗,研究组采用PICCO指导液体负平衡治疗,对比2组平均动脉压(MAP)、全心舒张末期容量指数(GED-CVI)、血清炎性因子水平[肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)]、急性生理与慢性健康状况评分(APACHEⅡ)、预后情况。结果治疗后3 d、治疗后6 d,研究组MAP水平较对照组高(P<0.05);治疗后3 d、治疗后6 d,研究组GED-CVI较对照组高(P<0.05);治疗后3 d、治疗后6 d,研究组血清TNF-α、IL-1β水平较对照组低(P<0.05);治疗后1 d、治疗后3 d、治疗后6 d,研究组APACHEⅡ评分较对照组低(P<0.05);研究组病死率2.70%(1/37)与对照组13.51%(5/37)对比无显著差异(P>0.05)。结论PICCO指导液体负平衡治疗感染性休克患者,可改善血压水平和心功能,缓解炎症状态,减轻病情严重程度,改善预后。
Objective To analyze the effect of PICCO on liquid negative balance for early recovery and prognosis in patients with septic shock.Methods 74 patients with septic shock in December 2020~December 2020,divided into study group(n=37)and control group(n=37),PICCO guided liquid negative balance treatment,compared two groups of mean arterial pressure(MAP),total end diastolic volume index(GED-CVI),serum inflammatory factor level[tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1β)]and prognosis.Results 3 days and 6 days after treatment,the MAP level in the study group was higher than that in the control group(P<0.05).3 days and 6 days after treatment,GED-CVI in the study group was higher than that in the control group(P<0.05).3 days and 6 days after treatment,the levels of TNF-αand IL-1βin the study group were lower than those in the control group(P<0.05).1 day,3 days and 6 days after treatment,the APACHEⅡscore of the study group was lower than that of the control group(P<0.05).There was no significant difference in mortality between 2.70%(1/37)of study group and 13.51%(5/37)of control group(P>0.05).Conclusion PICCO guides liquid negative balance in patients with infectious shock to improve blood pressure level and cardiac function,relieve inflammation and improve prognosis.
作者
古丽玲
Gu Liling(The People's Hospital of Xinfeng County,Xinfeng,Jiangxi341600)
出处
《基层医学论坛》
2021年第35期5038-5040,共3页
The Medical Forum
基金
赣州市指导性科技计划项目(GZ2020ZSF523)。
关键词
感染性休克
脉搏指示连续心排血量监测
液体负平衡治疗
平均动脉压
全心舒张末期容量指数
炎性因子
Septic shock
Pulse indication continuous cardiac volume monitoring
Liquid negative balance treatment
Mean arterial pressure
Total cardiac end diastolic volume index
Inflammatory factors
