摘要
目的分析内镜下黏膜切除术治疗结肠粗蒂性息肉的临床效果及复发影响因素。方法回顾性分析2018年5月—2021年3月收治的80例结肠粗蒂性息肉的临床资料,根据手术治疗方法不同,分为对照组38例和研究组42例。对照组行内镜下高频电切术,研究组行内镜下黏膜切除术。对比两组临床疗效、手术指标及并发症情况;影响患者复发的危险因素采用多因素Logistic回归分析。结果研究组临床总有效率高于对照组(P<0.05)。研究组手术时间、胃肠功能恢复时间、住院时间均短于对照组,术中出血量少于对照组(P<0.01)。研究组并发症发生率低于对照组(P<0.05)。经多因素Logistic回归分析,年龄、息肉大小、手术方式、组织学类型是影响结肠粗蒂性息肉患者复发的独立危险因素(P<0.01)。结论内镜下黏膜切除术治疗结肠粗蒂性息肉的临床效果显著,并发症少,安全性高。对于有结肠粗蒂性息肉复发危险因素的患者,需注意术后定期复查。
Objective To analyze clinical efficacy of endoscopic mucosal resection in treatment of patients with colonic polyps with thick pedicle and influencing factors of recurrence.Methods Clinical data of 80 patients with colonic polyps with thick pedicle admitted between May 2018 and March 2021 was retrospectively analyzed.The patients were divided into control group(n=38)and research group(n=42)according to different surgical methods.Control group underwent endoscopic high-frequency electroresection,while research group underwent endoscopic mucosal resection.Clinical efficacy,surgical indexes and incidence rate of complications were compared between two groups.Multivariate Logistic regression analysis was used to analyze risk factors of recurrence.Results The total effective rate in research group was significantly higher than that in control group(P<0.05).Compared with those in control group,operative duration,recovery time of gastrointestinal function and length of stay were significantly shorter,and the volume of intraoperative bleeding was less in research group(P<0.01).The incidence rate of complications in research group was lower than that in control group(P<0.05).Multivariate Logistic regression analysis showed that age,polyp size,operative method and histological type were independent risk factors for recurrence of colonic polyps with thick pedicle(P<0.01).Conclusion Endoscopic mucosal resection in treatment of patients with colonic polyps with thick pedicle may achieve significantly clinical effect,fewer complications and good safety.Patients with colonic polyps with thick pedicle having risk factor for recurrence should be warranted regular postoperative reexamination.
作者
邵长江
赵昌东
王淑芳
张秀敏
李雪
卢学峰
刘维忠
SHAO Chang-jiang;ZHAO Chang-dong;WANG Shu-fang;ZHANG Xiu-min;LI Xue;LU Xue-feng;LIU Wei-zhong(Department of Gastroenterology,the Second People's Hospital of Lianyungang,Lianyungang,Jiangsu 222000,China)
出处
《临床误诊误治》
CAS
2021年第12期59-63,共5页
Clinical Misdiagnosis & Mistherapy
基金
江苏省卫生健康委员会医学科研课题面上项目(H2018026)。
关键词
结肠息肉
内镜下黏膜切除术
手术后并发症
复发
危险因素
Colonic polyps
Endoscopic mucosal resection
Postoperative complications
Recurrence
Risk factors
