摘要
目的探究针对腹腔镜结直肠癌手术老年患者进行肺保护性通气策略,对其氧合功能与血清炎症介质的影响。方法选取南通大学附属肿瘤医院2020年3月至2021年4月收治的腹腔镜结直肠癌手术的老年患者76例,随机分为观察组和对照组,每组38例。观察组患者进行肺保护性通气的策略,对照组患者使用常规正压通气策略,比较两组患者在术中的氧合功能与血清炎症介质的参数变化,以及并发症发生率。结果两组患者的氧合功能比较,观察组均显著优于对照组(P<0.05);血清炎症介质比较,观察组显著优于对照组(P<0.05);观察组患者并发症发生率显著低于对照组(P<0.05)。结论肺保护性策略对进行结直肠癌腹腔镜手术的老年患者临床治疗效果显著,安全性高。
Objective To investigate the effect of lung protective ventilation strategy on oxygenation function and serum inflammatory mediators in elderly patients undergoing laparoscopic colorectal cancer surgery.Methods Seventy-six elderly patients undergoing laparoscopic colorectal cancer surgery in Cancer Hospital of Nantong University from March 2020 to April 2021 were randomly divided into observation group and control group,38 cases in each group.Patients in the observation group were treated with pulmonary protective ventilation strategy,and patients in the control group were treated with conventional positive pressure ventilation strategy.The changes of parameters of oxygenation function and serum inflammatory mediators during operation,as well as the incidence of complications,were compared between the two groups.Results In the data comparison of oxygenation function between the two groups,the observation group was significantly better than the control group(P<0.05);In the comparison of serum inflammatory mediators,the data of observation group was better than control group(P<0.05);The incidence of complications in observation group was significantly lower than that in control group(P<0.05).Conclusion Lung protective strategy has a significant effect on the clinical treatment of elderly patients undergoing laparoscopic surgery for colorectal cancer,with high safety.
作者
李鼎
张雷
江晓晖
LI Ding;ZHANG Lei;JIANG Xiaohui(Gastroenterology Department of Cancer Hospital of Nantong University,Nantong Cancer Hospital,Nantong 226361,Jiangsu;Anesthesiology Department of Cancer Hospital of Nantong University,Nantong Cancer Hospital,Nantong 226361,Jiangsu)
出处
《临床普外科电子杂志》
2021年第4期21-25,共5页
Journal of General Surgery for Clinicians(Electronic Version)
基金
南通市卫健委项目面上(MB2020025)
南通市科技计划指导性项目(JCZ20129)。
关键词
腹腔镜结直肠癌手术
肺保护性通气策略
氧合功能
血清炎症介质
老年
Laparoscopic colorectal surgery
Lung protective ventilation strategy
Oxygenation function
Serum inflammatory mediators
Elderly
