摘要
目的分析新疆地区维吾尔族、汉族糖尿病与结肠息肉发病关联性。方法选择于新疆维吾尔自治区人民医院就诊,结肠镜检查确诊结肠息肉的汉族及维吾尔族糖尿病患者680例为研究对象(糖尿病组),无糖尿病患者680例为对照(非糖尿病组),对其一般情况、高风险状态及民族差异进行分析。结果维吾尔族患者结肠息肉发病年龄为(52.60±11.80)岁,明显小于汉族患者的发病年龄(59.95±12.63)岁,差异有统计学意义(t=5.52,P<0.05)。糖尿病组体重指数(27.45±3.38)kg/m^(2)高于非糖尿病组(23.76±5.69)kg/m^(2),差异有统计学意义(t=15.95,P<0.05)。两组血压比较差异无统计学意义(P>0.05)。糖尿病组甘油三酯(1.90±0.48)mmol/L高于非糖尿病组(1.19±0.34)mmol/L,差异有统计学意义(t=13.52,P<0.05)。糖尿病组排便习惯改变例数(120例)多于非糖尿病组(68例),差异有统计学意义(χ^(2)=16.69,P<0.05)。糖尿病组高风险息肉检出百分比(2.8%)高于非糖尿病组(1.6%),但差异无统计学意义(χ^(2)=1.62,P>0.05)。结论新疆地区维吾尔族结肠息肉患者发病年龄较汉族小,糖尿病在汉族及维吾尔族结肠息肉的临床表现有关系,与息肉高风险状态无明显关系。
Objective To assess the association of diabetes mellitus with colonic polyps in Uygur Han people in Xinjiang.Methods A total of 680 Han and Uygur diabetic patients with colon polyps diagnosed by colonoscopy in Xinjiang Uygur Autonomous Region were enrolled. 680 non-diabetic patients were selected as controls and their general conditions,highrisk status and ethnic differences were analyzed. Results The age of onset of Uyghur patients was(52.60±11.80)years old,which was significantly lower than that of Han patients(59.95 ± 12.63)years old. The difference was statistically significant(t=5.52,P<0.05). Those with diabetes had higher BMI(27.45±3.38)kg/m^(2)than those of without diabetes(23.76±5.69)kg/m^(2),and the difference was statistically significant(t=15.95,P<0.05). There was no statistical difference in blood pressure between the two groups. The two groups had higher levels of triglyceride(1.90±0.48)mmol/L than those without diabetes(1.19±0.34)mmol/L and the difference was statistically significant(t=13.52,P<0.05). The clinical manifestations of bowel habits were changed. There were more cases with diabetes than without diabetes(120 vs. 68). The difference was statistically significant(χ^(2)=16.69,P<0.05). Compared with the percentage of high-risk polyps in the two groups,in the diabetic group was higher than that in the non-diabetic group(2.8% vs. 1.6%),but the difference was not statistically significant(χ^(2)=1.62,P>0.05). Conclusions The age of onset of Uyghur colonic polyps in Xinjiang was younger than that of the Han nationality. Diabetes had a certain correlation with colon polyps in Han and Uyghur. However,it had no significant relationship with high risk status of polyps.
作者
古丽加那提·马斯开
李凤
阿依努尔·阿合曼
Gulijianati Masikai;LI Feng;Ayinuer Aheman(Department of Geriatrics,Endocrinology,Second Affiliated Hospital of Xinjiang Medical University,Urumqi,Xinjiang 830028;Department of Gastroenterology,People’s Hospital of Xinjiang Uygur Autonomous Region,Urumqi,Xinjiang 830001,China)
出处
《热带医学杂志》
CAS
2021年第10期1332-1334,共3页
Journal of Tropical Medicine
基金
乌鲁木齐市科学技术计划项目(Y141310022)。
