摘要
目的探讨匹多莫德治疗儿童呼吸系统反复感染的临床效果。方法60例儿童呼吸系统反复感染患儿,采用随机数字表法分为对照组和实验组,每组30例。对照组给予常规治疗,实验组在常规治疗基础上给予匹多莫德治疗。比较两组患儿治疗前后白细胞计数、降钙素原、C反应蛋白水平,治疗效果,肺部啰音消失时间、咳嗽消失时间、发热消失时间。结果治疗后,两组患儿的白细胞计数、降钙素原、C反应蛋白水平均较治疗前改善,且实验组白细胞计数、降钙素原、C反应蛋白水平低于对照组,差异具有统计学意义(P<0.05)。实验组患儿的治疗总有效率100.00%高于对照组的73.33%,差异具有统计学意义(P<0.05)。实验组肺部啰音消失时间(5.45±1.62)d、咳嗽消失时间(6.34±1.43)d、发热消失时间(2.01±0.12)d均短于对照组的(7.77±2.45)、(8.45±2.64)、(3.72±0.33)d,差异具有统计学意义(P<0.05)。结论儿童呼吸系统反复感染患儿给予匹多莫德治疗效果确切。
Objective To discuss the clinical effect of pidotimod in the treatment of repeated infections of the respiratory system in children.Methods A total of 60 children with repeated infections of the respiratory system were divided into control group and experimental group according to random numerical table,with 30 cases in each group.The control group was treated with conventional therapy,and the experimental group was treated with pidotimod on the basis of the conventional therapy.Both groups were compared in terms of white blood cell count,procalcitonin,C-reactive protein before and after treatment,therapeutic effect,disappearance time of lung rales,disappearance time of cough,and disappearance time of fever.Results After treatment,the white blood cell count,procalcitonin,and C-reactive protein of the two groups were better than those of this group before treatment,and the experimental group was lower than the control group.All the differences were statistically significant(P<0.05).The total effective rate of treatment 100.00%of the experimental group was higher than 73.33%of the control group,and the difference was statistically significant(P<0.05).The disappearance time of lung rales,cough and fever of the experimental group were(5.45±1.62),(6.34±1.43)and(2.01±0.12)d,which were shorter than(7.77±2.45),(8.45±2.64)and(3.72±0.33)d of the control group,and the difference was statistically significant(P<0.05).Conclusion Pidotimod has definite effect on children with repeated infections of the respiratory system.
作者
王秀丽
WANG Xiu-li(Xinmin Maternity and Infant Hospital,Xinmin 110300,China)
出处
《中国实用医药》
2021年第33期127-129,共3页
China Practical Medicine
关键词
儿童
呼吸系统反复感染
匹多莫德
降钙素原
C反应蛋白
Children
Repeated infections of the respiratory system
Pidotimod
Procalcitonin
C-reactive protein
