摘要
目的探讨阴道彩色多普勒超声检查联合血清人绒毛膜促性腺激素(HCG)、孕酮水平测定对孕早期患者妊娠结局的预测价值。方法选取2019年1月至2020年1月收治的200例存在高危因素的孕早期患者作为研究对象,采用计算机数字随机模型将其分为对照组和观察组,各100例。对照组行阴道彩色多普勒超声检查,观察组在对照组基础上联合血清HCG、孕酮水平测定。比较两组的胚胎发育异常率、早期流产率。比较不良妊娠患者与正常妊娠患者的双侧子宫动脉参数及血清HCG、孕酮、雌二醇水平。分析不同方式对不良妊娠的诊断价值。结果观察组的胚胎发育异常率高于对照组,早期流产率低于对照组(P<0.05)。不良妊娠患者的PSV及血清HCG、孕酮、雌二醇水平低于正常妊娠患者,RI、PI高于正常妊娠患者(P<0.05)。阴道彩色多普勒超声检查联合血清HCG、孕酮水平测定对不良妊娠的诊断灵敏度、准确度均高于单一阴道彩色多普勒超声检查及血清HCG、孕酮水平测定(P<0.05)。结论阴道彩色多普勒超声检查及血清HCG、孕酮水平测定可预测孕早期患者的妊娠结局,能够判断胚胎发育异常,在不良妊娠诊断中具有较高的价值。
Objective To investigate the predictive value of transvaginal color doppler ultrasound examination combined with serum human chorionic gonadotropin(HCG)and progesterone levels determination in pregnancy outcome of early pregnancy patients.Methods A total of 200 early pregnancy patients with high-risk factors treated from January 2019 to January 2020 were selected as the research objects.The patients were divided into control group and observation group by computer digital random model,with 100 cases in each group.The control group was given transvaginal color doppler ultrasound examination,and the observation group was combined with serum HCG and progesterone levels determination on the basis of the control group.The abnormal embryonic development rate and early abortion rate were compared between the two groups.The parameters of bilateral uterine arteries and serum HCG,progesterone and estradiol levels were compared between patients with adverse pregnancy and normal pregnancy.The diagnostic value of different methods for adverse pregnancy were analyzed.Results The abnormal embryonic development rate in the observation group was higher than that in the control group,and the early abortion rate was lower than that in the control group(P<0.05).The PSV,serum HCG,progesterone and estradiol levels in patients with adverse pregnancy were lower than those in patients with normal pregnancy,and RI and PI were higher than those in patients with normal pregnancy(P<0.05).The sensitivity and accuracy of transvaginal color doppler ultrasound examination combined with serum HCG and progesterone levels determination in the diagnosis of adverse pregnancy were higher than those of single transvaginal color doppler ultrasound examination and serum HCG and progesterone levels determination(P<0.05).Conclusion Transvaginal color doppler ultrasound examination combined with serum HCG and progesterone levels determination can predict the pregnancy outcome of early pregnancy patients,judge abnormal embryonic development,and have high val
作者
周季君
李娜
何文丽
ZHOU Jijun;LI Na;HE Wenli(Tianjin Hospital of Ningqiang County,Hanzhong 724400;No.215 Hospital of Shaanxi Nuclear Industry,Xianyang 712000;Xianyang Hospital of Yan'an University,Xianyang 712000,China)
出处
《临床医学研究与实践》
2021年第35期120-122,共3页
Clinical Research and Practice
关键词
阴道彩色多普勒超声
血清人绒毛膜促性腺激素
孕酮
妊娠结局
transvaginal color doppler ultrasound
serum human chorionic gonadotropin
progesterone
pregnancy outcome
